Visible-light photoredox-catalyzed method has been developed for the synthesis of quinoxalin-2(1)-one-containing vinyl phosphorodithioates via direct difunctionalization of alkynes with quinoxalin-2(1)-ones, PS and alcohols. This four-component reaction could be carried out under metal-free and mild conditions, affording a number of quinoxalin-2(1)-one-containing vinyl phosphorodithioates in moderate to good yields with Z-isomers as the major products. Photocatalytic radical mechanism is proposed based on the results of radical trapping and fluorescence quenching experiments.
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| http://dx.doi.org/10.1021/acs.joc.4c01409 | DOI Listing |
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