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Background: A chronic inflammatory state characterizes a wide range of diseases for which obesity is a risk factor. Weight loss could reduce levels of circulating inflammatory markers potentially reducing the incidence of associated diseases and improving response to treatment. However, dietary weight loss studies have reported inconsistent effects on serum inflammatory makers and the long-term effects are unknown.
View Article and Find Full Text PDFScreening and assessment of falls risk in the emergency department.
Australas Emerg Care
March 2025
Emergency Department, The Prince Charles Hospital, Rode Rd, Chermside, Queensland 4032, Australia. Electronic address:
Background: Falls are a source of harm, repeat emergency department visits and hospital admission for older adults. Undertaking a comprehensive geriatric screening including falls-risk is recommended in guidelines for optimal older adult emergency department care.
Methods: A pragmatic prospective cohort study was undertaken to evaluate use of further falls-risk screening in older adults in a large tertiary Australian hospital emergency department.
Vaccines and the risk of Guillain-Barré syndrome: A French pharmacovigilance analysis.
Therapie
March 2025
Département de pharmacologie, AP-HP, GHU Sorbonne université, centre régional de pharmacovigilance Pitié-Saint-Antoine, 75000 Paris, France. Electronic address:
Aims: Guillain-Barré syndrome (GBS) is a rare autoimmune-mediated disease that can occur in a post-vaccination context. During the vaccination surveillance program of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines, reports of GBS as a possible adverse effect (AE) of SARS-CoV-2 vaccines have been reported. Our aim was to describe post-vaccine reports of GBS whatever the vaccine used.
View Article and Find Full Text PDFBrain health PRO/Santé cerveau PRO: The development of a web-based program for dementia literacy and risk factor reduction.
J Prev Alzheimers Dis
March 2025
Department of Neurosciences, University of California, San Diego, California, USA; Alzheimer's Disease Cooperative Study, School of Medicine, University of California. San Diego California USA.
Background: Online educational programs focused on ways to improve brain health could increase participant literacy, empowerment, and engagement in activities that support personal brain health, potentially reducing dementia risk.
Objectives: Our goal was to develop an evidence-based online educational program with a focus on risk and protective factors for dementia. Here we present the rationale and features of the program and include results from a pilot study that assessed usability and acceptability.
The Choice of Hip Arthroplasty: HRA or THA? Revealed by Meta-Analysis.
Orthop Surg
March 2025
Department of Orthopaedics, Qingdao Municipal Hospital, Qingdao, China.
Background: Total hip arthroplasty (THA) is the gold standard for end-stage hip arthrosis, while hip resurfacing arthroplasty (HRA) is considered a more bone-conserving alternative. This meta-analysis aimed to compare the safety and clinical efficacy of HRA and THA.
Methods: The databases of PubMed, EMBASE, Cochrane Library, and CNKI were searched for RCTs comparing HRA and THA in treating hip arthrosis from database initiation to April 2024.
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