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[Right ventricle-dependent coronary circulation in pulmonary atresia with intact ventricular . About three patients without coronary ostium atresia. Is a transient percutaneous decompression maneuver necessary?].
Arch Cardiol Mex
November 2024
Departamento de Cardiología Pediátrica, Instituto Nacional de Pediatría, Ciudad de México, México.
Objective: Pulmonary atresia with intact ventricular septum (PA-IVS) is a rare congenital heart disease characterized by a wide morphological spectrum that can be associated with abnormalities in the coronary circulation such as sinusoids, fistulas, stenosis or atresia. Some patients do not present ventriculo-coronary fistulas or intramyocardial sinusoids, other patients do present ventriculo-coronary connections, but only some of the latter will have right ventricle-dependent coronary circulation (RVDCC); timely establishment of the diagnosis of RVDCC is essential, since the prognosis of these patients is generally fatal. There are reports of patients with this type of coronary circulation (RVDCC) who were undergone to univentricular physiology, but this treatment option remains controversial, so the purpose of this manuscript is to share three cases with PA-IVS and RVDCC, their outcome and the reflections they provide us.
View Article and Find Full Text PDFIntramyocardial and intra-atrial courses in the right coronary artery: prevalence and characteristics.
Int J Cardiovasc Imaging
December 2024
Department of Radiology, Etlik City Hospital, Halil Sezai Erkut Street, Etlik, Ankara, Turkey.
Purpose: We aimed to determine the prevalence and radiological characteristics of myocardial bridging (MB) and intra-atrial course anomaly (IARCA), which are rare course variations of the right coronary artery (RCA), in the adult patient population.
Methods: Radiological images of cases over the age of 18 who underwent coronary CT angiography (CTA) examination in our clinic were scanned from the archives retrospectively, and cases with MB of the RCA and IARCA detection were included in the study. The number, age and gender distribution of the cases, whether there were any other accompanying vascular anomalies, whether there was atherosclerosis in the coronary arteries (calculation of Agatston total calcium score, calculation of atherosclerotic stenosis as a percentage, if any) were evaluated.
Fatal intramyocardial dissecting haematoma caused by coronary artery perforation during percutaneous coronary intervention.
Eur Heart J Imaging Methods Pract
January 2024
Department of Diagnostic Pathology, Miyazaki Medical Association Hospital, Miyazaki, Japan.
Long-Term Prognostic Value of Infarct Transmurality Determined by Contrast-Enhanced Cardiac Magnetic Resonance after ST-Segment Elevation Myocardial Infarction.
Chonnam Med J
May 2024
Department of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
The long-term prognostic significance of maximal infarct transmurality evaluated by contrast-enhanced cardiac magnetic resonance (CE-CMR) in ST-segment elevation myocardial infarction (STEMI) patients has yet to be determined. This study aimed to see if maximal infarct transmurality has any additional long-term prognostic value over other CE-CMR predictors in STEMI patients, such as microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH). The study included 112 consecutive patients who underwent CE-CMR after STEMI to assess established parameters of myocardial injury as well as the maximal infarct transmurality.
View Article and Find Full Text PDFTransient induction of actin cytoskeletal remodeling associated with dedifferentiation, proliferation, and redifferentiation stimulates cardiac regeneration.
Acta Pharm Sin B
June 2024
Department of Cardiology, Daping Hospital, the Third Military Medical University (Army Medical University), Chongqing 400042, China.
The formation of new and functional cardiomyocytes requires a 3-step process: dedifferentiation, proliferation, and redifferentiation, but the critical genes required for efficient dedifferentiation, proliferation, and redifferentiation remain unknown. In our study, a circular trajectory using single-nucleus RNA sequencing of the pericentriolar material 1 positive (PCM1) cardiomyocyte nuclei from hearts 1 and 3 days after surgery-induced myocardial infarction (MI) on postnatal Day 1 was reconstructed and demonstrated that actin remodeling contributed to the dedifferentiation, proliferation, and redifferentiation of cardiomyocytes after injury. We identified four top actin-remodeling regulators, namely , , , and , which we collectively referred to as 2D2P.
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