Aims: Suture-mediated patent fossa ovalis (PFO) closure is a recent technique, achieving closure by means of a simple suture. The differences between traditional occluders and suture might have different impacts on atrial function. The aim of this study was to evaluate atrial function after PFO closure by direct suture and traditional occluders.
Methods And Results: We prospectively studied 40 patients, 20 undergoing PFO closure by occluder and 20 by suture. Trans-thoracic echocardiography was carried out the day before and 1 year after the procedure. Left atrial (LA) and right atrial (RA) function was evaluated by using speckle-tracking analysis assessing the strain values of the reservoir (st-RES), conduit (st-CD), and contraction phase (st-CT). Compared with values baseline PFO closure, at 1-year follow-up, patients with occluder implantation had significantly worse indices of LA and RA reservoir (LA st-RES < 0.001; RA st-RES < 0.001), conduit (LA st-CD < 0.001; RA st-CD < 0.001), and contraction function (LA st-CT < 0.05; RA st-CT < 0.05). In patients with suture-mediated PFO closure, no significant differences were observed in the same indices of reservoir (LA st-RES = 0.848; RA st-RES = 0.183), conduit (LA st-CD = 0.156; RA st-CD = 0.419), and contraction function (LA st-CT = 0.193; RA st-CT = 0.375).
Conclusion: Suture-mediated PFO closure does not alter atrial function. Conversely, PFO closure by metallic occluders is associated with a deterioration of atrial function. This detrimental effect on atrial function could favour the development of atrial arrhythmias.
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| http://dx.doi.org/10.1093/ehjimp/qyae008 | DOI Listing |
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