AI Article Synopsis
- Socket preservation is a surgical technique used to maintain alveolar bone dimensions after tooth extraction, with recent studies exploring the use of extracted dentine as an autograft material.
- A systematic review protocol is being developed to assess the effectiveness of dentine compared to traditional bone grafts, focusing on randomized and non-randomized studies that utilize this material for socket preservation.
- The findings will help inform dental clinicians and patients about using dentine as a less invasive option for bone regeneration, turning what is often considered waste into a valuable resource.
Article Abstract
Background: Socket preservation is a surgical procedure aimed at preserving the dimensions of the alveolar bone following tooth extraction. It is performed by filling the extraction socket with bone graft material with or without a barrier membrane. Recently, dentine obtained from extracted teeth has been tried as an autograft for socket preservation. Studies have compared the use of dentin to other bone grafts, however, systematic reviews evaluating the efficacy of dentin for socket preservation are limited. Hence, this systematic review protocol is proposed to generate evidence on the efficacy of dentin as a viable alternative to other bone graft materials for socket preservation.
Methods: This systematic review protocol was prepared according to the Methodological Expectations of the Cochrane Intervention Reviews (MECIR) guidelines. It will be conducted using the Cochrane Handbook for Systematic Review of Interventions. PubMed, Scopus, Web of Science, EMBASE, Epistemonikos, Cochrane Central, and EBSCO databases and clinical trial registries, will be searched for all randomized controlled trials (RCTs) and non-randomized studies that have used autologous dentin graft (either in particulate/putty, or/matrix form) for socket preservation. The radiographic and clinical assessment of bone and soft tissue healing of the preserved sockets along with patient-related outcomes following surgery will be assessed. The risk of bias assessment of the RCTs and Non-RCTs will be assessed using the 'Cochrane Risk of Bias assessment tool (ROB II) and ROBINS-I respectively. The certainty of evidence will be assessed by the GRADE approach.
Discussion: This evidence is important for dental clinicians and the public to make an informed decision when choosing graft material for socket preservation. The extracted teeth are considered biological waste; however, this evidence provides scope for using a less invasive autograft for bone regenerative procedures.
Systematic Review Registration: PROSPERO: CRD42021201958 (Registered on 15/02/2021).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11263907 | PMC |
| http://dx.doi.org/10.12688/f1000research.144522.1 | DOI Listing |
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