AI Article Synopsis

  • Juvenile pityriasis rubra pilaris is a rare inflammatory skin condition that currently lacks FDA-approved treatments and can be tough to manage with standard therapies.
  • A 6-year-old boy achieved clear skin within 2 weeks after starting ixekizumab therapy, which has remained effective for 6 months.
  • This case suggests ixekizumab could be a promising and quick treatment option for children suffering from this rare skin disorder.

Article Abstract

Juvenile pityriasis rubra pilaris is a rare inflammatory skin disorder currently without any FDA-approved treatments, and lesions can be refractory to conventional treatment with topical corticosteroids, methotrexate, and oral retinoids. We herein present a case of a 6-year-old boy who attained clearance of extensive juvenile pityriasis rubra pilaris within 2 weeks of starting ixekizumab therapy. Therapeutic effect has been durable at 6 months, and patient continues on therapy without adverse effects. Our case highlights a new, rapidly effective treatment option for pediatric patients with this rare condition.

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http://dx.doi.org/10.1111/pde.15700DOI Listing

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