Juvenile pityriasis rubra pilaris is a rare inflammatory skin disorder currently without any FDA-approved treatments, and lesions can be refractory to conventional treatment with topical corticosteroids, methotrexate, and oral retinoids. We herein present a case of a 6-year-old boy who attained clearance of extensive juvenile pityriasis rubra pilaris within 2 weeks of starting ixekizumab therapy. Therapeutic effect has been durable at 6 months, and patient continues on therapy without adverse effects. Our case highlights a new, rapidly effective treatment option for pediatric patients with this rare condition.
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http://dx.doi.org/10.1111/pde.15700 | DOI Listing |
Pediatr Dermatol
November 2024
Harvard Medical School, Boston, Massachusetts, USA.
Skin Appendage Disord
April 2024
Department of Dermatology and STD, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
J Eur Acad Dermatol Venereol
June 2024
Department of Dermatology, University-Hospital Tuebingen, Tuebingen, Germany.
Dermatol Pract Concept
April 2023
Traditional Chinese Medicine Hospital of Shangyu, Shaoxing, China.
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