[Advances in bioinformatics-based protein function prediction].

Sheng Wu Gong Cheng Xue Bao

School of Information Science and Engineering, University of Jinan, Jinan 250022, Shandong, China.

Published: July 2024

AI Article Synopsis

  • The rise in computer power and biological data has made bioinformatics essential for solving biological issues, particularly in drug discovery and biomedical research.
  • This paper classifies protein function prediction methods into three main types: sequence-based, structure-based, and interaction networks-based.
  • It analyzes recent advancements in these algorithms, offering insights and references for applying bioinformatics in protein function prediction.

Article Abstract

With the increasing of computer power and rapid expansion of biological data, the application of bioinformatics tools has become the mainstream approach to address biological problems. The accurate identification of protein function by bioinformatics tools is crucial for both biomedical research and drug discovery, making it a hot topic of research. In this paper, we categorize bioinformatics-based protein function prediction methods into three categories: protein sequence-based methods, protein structure-based methods, and protein interaction networks-based methods. We further analyze these specific algorithms, highlighting the latest research advancements and providing valuable references for the application of bioinformatics-based protein function prediction in biomedical research and drug discovery.

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Source
http://dx.doi.org/10.13345/j.cjb.230675DOI Listing

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