Sex-related differences regarding headache triggered by low barometric pressure in Japan.

BMC Res Notes

Division of Social Pharmacy, Center for Social Pharmacy and Pharmaceutical Care Sciences, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, 105-8512, Japan.

Published: July 2024

AI Article Synopsis

  • The study investigates how sex-related differences impact migraine headaches triggered by low barometric pressure, which affects women more frequently than men.
  • Researchers analyzed data from 669 participants (332 women and 337 men) aged 20-49, focusing on the association between high headache impact scores and being triggered by low barometric pressure.
  • Results indicate that headaches triggered by low barometric pressure are significantly more common in women, suggesting the need for sex-specific treatment strategies for migraines.

Article Abstract

Purpose: The prevalence of migraine headache is higher in women. Low barometric pressure is a factor in headache triggering, but sex-related differences have not been identified. The purpose of this study was to examine sex-related differences in headache triggered by low barometric pressure.

Methods: Study subjects aged 20-49 years were randomly selected from a research company's (Macromill, Inc.) web panel. Those with chronic migraine or tension-type headache invited to complete a web-based self-administered questionnaire. Logistic regression analysis was performed with the objective variable as the Headache Impact Test-6 (HIT-6) high scores (56 or more) or headache triggered by low barometric pressure.

Results: Participants were 332 women and 337 men in the headache population. HIT-6 high scores were associated with age at headache occurrence 20 years or younger (OR: odds ratio 1.85, 95% CI: confidence interval 1.15-2.99, p = 0.012) and headache triggered by low barometric pressure (OR 2.11, 95%CI 1.51-2.94, p < 0.001). Headache triggered by low barometric pressure was significantly associated with women (OR 2.92, 95%CI 2.12-4.02, p < 0.001).

Conclusions: Headache triggered by low barometric pressure were related to sex-related differences. It was suggested that a sex-specific treatment approach for headache triggering is needed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11267689PMC
http://dx.doi.org/10.1186/s13104-024-06827-3DOI Listing

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