Preiser's disease or idiopathic avascular necrosis of the scaphoid is a rare condition where ischemia and necrosis of the scaphoid bone occurs without previous fracture. It is thought to be caused by repetitive micro trauma or side effects of drugs (e.g., steroids or chemotherapy) in conjunction with existing defective vascular supply to the proximal pole of the scaphoid. Wrist radiography or CT coupled with MRI is the imaging modality of choice in the diagnosis of this rare entity. Here, we report a case of Preiser's disease of the left wrist in a 17-year-old female patient who presented with left wrist pain of 2 years duration in the absence of trauma history or causative drug use. The diagnosis was made by wrist X-ray and MRI. She was managed by Physiotherapy and wrist immobilization using wrist and forearm support as well as NSAIDS (Meloxicam).
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http://dx.doi.org/10.1016/j.radcr.2024.06.008 | DOI Listing |
Allergy
December 2024
Service de Pneumologie, Centre Hospitalier Universitaire UCL Namur, Université Catholique de Louvain, Yvoir, Belgium.
Background: Exposure-related changes in exhaled nitric oxide (FeNO) and sputum eosinophils have not been thoroughly compared in the investigation of occupational asthma.
Objective: This study aimed at comparing the accuracies of the changes in FeNO concentrations and sputum eosinophil counts in identifying asthmatic reactions induced by occupational agents during specific inhalation challenges (SICs).
Methods: This retrospective multicenter study included 321 subjects who completed an assessment of FeNO and sputum eosinophils before and 24 h after SICs with various occupational agents, of whom 156 showed a positive result.
Int J Mol Sci
October 2024
Centre for Epidemic Response and Innovation (CERI), Stellenbosch University, Stellenbosch 7600, South Africa.
Chronic Hepatitis B Virus (HBV) infection remains a significant public health concern, particularly in Africa, where the burden is substantial. HBV is an enveloped virus, classified into ten phylogenetically distinct genotypes (A-J). Tests to determine HBV genotypes are based on full-genome sequencing or reverse hybridization.
View Article and Find Full Text PDFS Afr J Infect Dis
August 2024
Pathogen Research Laboratory, Division of Virology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
J Glob Antimicrob Resist
December 2024
German Leprosy and Tuberculosis Relief Association (DAHW), Würzburg, Germany; Medmissio, Würzburg, Germany.
Background: Prospective data on the effectiveness of resistance testing in informing treatment decisions and outcomes in with first-line failure in these settings is limited. This study aimed to assess the virological impact of HIV drug-resistance testing in patients with virological failure in Tanzania.
Methods: Participants were randomly assigned to either the control or the experimental group.
J Hand Surg Glob Online
July 2024
Department of Orthopaedic Surgery, Niigata Hand Surgery Foundation, Kitakambara, Japan.
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