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Material-based treatment strategies against intraosseous implant biofilm infection. | LitMetric

Material-based treatment strategies against intraosseous implant biofilm infection.

Biochem Biophys Rep

Department of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, PR China.

Published: September 2024

Implant-associated infections present a significant clinical obstacle for orthopedic practitioners, with bacterial biofilm formation serving as a pivotal factor in the initiation, progression, and management of such infections. Conventional approaches have proven inadequate in fully eradicating biofilm-related infections. Consequently, novel material-based therapeutic strategies have been developed, encompassing the utilization of antimicrobial agents, delivery vehicles, and synergistic antibacterial systems. In this review, we provide a succinct overview of recent advancements in anti-biofilm strategies, with the aim of offering insights that may aid in the treatment of intraosseous implant infections.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11261528PMC
http://dx.doi.org/10.1016/j.bbrep.2024.101764DOI Listing

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