Cognition and communication in patients with spinal muscular atrophy: A systematic review.

Heliyon

Université Libre de Bruxelles, ULB, Hôpital Universitaire de Bruxelles (HUB), Hôpital Universitaire des Enfants Reine Fabiola (HUDERF), Department of Paediatric Neurology and Neuromuscular Reference Center, Brussels, Belgium.

Published: July 2024

•Synthesizes evidence from 12 studies on cognitive and communicative impacts in SMA, focusing on nuanced functional outcomes.•Highlights cognitive variability in SMA1, revealing subtle challenges in SMA2 and 3, and stresses tailored assessment methodologies.•Identifies communication barriers in SMA, emphasizing the urgency of investigating their potential interplay with cognitive functions.•Stresses integrating cognitive and communicative assessments into SMA management, to enhanceunderstanding of treatment impacts.•Calls for standardized, sensitive tools to evaluate cognition and communication, ensuring consistent assessments across SMA phenotypes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11261103PMC
http://dx.doi.org/10.1016/j.heliyon.2024.e33677DOI Listing

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