Light-based 3D bioprinting technology applied to repair and regeneration of different tissues: A rational proposal for biomedical applications.

Mater Today Bio

Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.

Published: August 2024

AI Article Synopsis

  • * It emphasizes the importance of choosing the right photosensitive polymers and adjusting various parameters, like light exposure and specific chemical components, to create scaffolds that meet the needs of different tissues.
  • * Lastly, the review provides insights into different bio-inks, strategies for selecting materials for specific repairs, and methods for optimizing the printing process, while also discussing challenges and future developments in the technology.

Article Abstract

3D bioprinting technology, a subset of 3D printing technology, is currently witnessing widespread utilization in tissue repair and regeneration endeavors. In particular, light-based 3D bioprinting technology has garnered significant interest and favor. Central to its successful implementation lies the judicious selection of photosensitive polymers. Moreover, by fine-tuning parameters such as light irradiation time, choice of photoinitiators and crosslinkers, and their concentrations, the properties of the scaffolds can be tailored to suit the specific requirements of the targeted tissue repair sites. In this comprehensive review, we provide an overview of commonly utilized bio-inks suitable for light-based 3D bioprinting, delving into the distinctive characteristics of each material. Furthermore, we delineate strategies for bio-ink selection tailored to diverse repair locations, alongside methods for optimizing printing parameters. Ultimately, we present a coherent synthesis aimed at enhancing the practical application of light-based 3D bioprinting technology in tissue engineering, while also addressing current challenges and future prospects.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262185PMC
http://dx.doi.org/10.1016/j.mtbio.2024.101135DOI Listing

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