Background: Caesarean section is a widely performed surgical procedure that often results in moderate-to-severe postoperative pain. If left untreated, this pain can lead to short-term and long-term consequences. Transversalis fascia plane (TFP) block and transversus abdominis plane (TAP) block are among the regional anaesthesia techniques employed for managing pain after a caesarean section.
Objective: We aimed to compare the impact of these two blocks on the quality of recovery in patients undergoing elective caesarean section under spinal anaesthesia.
Design: A single-centre, double-blind, randomised trial.
Settings: Operating room, postanaesthesia recovery unit, and ward in a tertiary hospital.
Participants: Ninety-three patients (ASA 2 to 3) were recruited. After exclusion, 79 patients were included in the final analysis: 40 in the TFP block group and 39 in the TAP block group.
Interventions: After surgery, participants received either TFP block (20 ml 0.25% bupivacaine for each side) or TAP block (20 ml 0.25% bupivacaine for each side).
Main Outcome Measures: The primary outcome was the difference in obstetric quality of recovery 11-Turkish (ObsQoR-11T) scores between groups. Secondary outcomes included pain scores, opioid consumption and incidence of opioid-related complications.
Results: The mean ObsQoR-11T score was higher in the TFP block group compared with the TAP block group (97.13 ± 6.67 points vs. 87.10 ± 9.84 points, respectively; P < 0.001). The pain scores in the TFP block group were slightly lower between postoperative 4 and 24 h. The mean total morphine consumption was 15.08 ± 2.21 mg in the TFP block group and 22.21 ± 3.04 mg in the TAP block group ( P < 0.001). More patients required rescue analgesia between 4 and 8 h in the TAP block group [2.00 (5.00%) vs. 9.00 (23.08%), P = 0.02]. No significant differences were observed between groups in terms of opioid-related side effects.
Conclusion: TFP block used for analgesic purposes yielded a better quality recovery period than TAP block and also reduced opioid consumption.
Trial Registration: Clinicaltrials.gov (NCT05999981).
Visual Abstract: http://links.lww.com/EJA/B6 .
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http://dx.doi.org/10.1097/EJA.0000000000002041 | DOI Listing |
Talanta
December 2024
College of Chemistry, Jilin University, Changchun, 130012, PR China. Electronic address:
Cir Cir
November 2024
Department of Anesthesiology and Reanimation, Ataturk University School of Medicine, Erzurum, Turkey.
Objective: The post-operative analgesic efficacy of transversalis fascia plane (TFP) block is controversial in pediatric patients undergoing herniotomy. This study aims to compare the efficacy of TFP block and standard analgesic methods.
Methods: Sixty patients aged 1-8 years who underwent the open procedure of herniotomy were randomly divided into two groups TFP block (n = 30) or control group (n = 30).
JCI Insight
September 2024
Genetic and Genomic Medicine Division, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh.
Mitochondrial trifunctional protein (TFP) deficiency is an inherited metabolic disorder leading to a block in long-chain fatty acid β-oxidation. Mutations in HADHA and HADHB, which encode the TFP α and β subunits, respectively, usually result in combined TFP deficiency. A single common mutation, HADHA c.
View Article and Find Full Text PDFEur J Anaesthesiol
October 2024
From the Department of Anaesthesiology and Reanimation, Muğla Sitki Koçman University Faculty of Medicine (AP, BA, MKT, BU) and Department of Gynaecology and Obstetrics, Muğla Sitki Koçman University Faculty of Medicine, Muğla, Türkiye (FP).
Background: Caesarean section is a widely performed surgical procedure that often results in moderate-to-severe postoperative pain. If left untreated, this pain can lead to short-term and long-term consequences. Transversalis fascia plane (TFP) block and transversus abdominis plane (TAP) block are among the regional anaesthesia techniques employed for managing pain after a caesarean section.
View Article and Find Full Text PDFNanoscale
June 2024
Louvain Institute of Biomolecular Science and Technology, UCLouvain, Croix du Sud, 4-5, L7.07.07, B-1348 Louvain-la-Neuve, Belgium.
Type IV pili (TFP) contribute to the ability of microbes such as to engage with and move across surfaces. We reported previously that TFP generate retractive forces of ∼30 pN and provided indirect evidence that TFP-mediated surface attachment was enhanced in the presence of the Pel polysaccharide. Here, we use different mutants defective in flagellar, Pel production or TFP production - alone or in combination - to decipher the relative contribution of these biofilm-promoting factors for adhesion.
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