AI Article Synopsis
- Xeno nucleic acids (XNA) are synthetic nucleic acids with altered sugar components, giving them unique physical and chemical traits.
- These modifications enhance their biological stability and change how they interact with other molecules.
- The article reviews these unique properties of XNAs and discusses their potential uses across different fields as innovative materials.
Article Abstract
Xeno nucleic acid (XNA) are artificial nucleic acids, in which the chemical composition of the sugar moiety is changed. These modifications impart distinct physical and chemical properties to XNAs, leading to changes in their biological, chemical, and physical stability. Additionally, these alterations influence the binding dynamics of XNAs to their target molecules. Consequently, XNAs find expanded applications as functional materials in diverse fields. This review provides a comprehensive summary of the distinctive biophysical properties exhibited by various modified XNAs and explores their applications as innovative functional materials in expanded fields.
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| http://dx.doi.org/10.1002/adhm.202401207 | DOI Listing |
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