AI Article Synopsis
- Schwannomas are benign tumors that arise from Schwann cells in the peripheral nervous system, featuring both dense (Antoni A) and looser (Antoni B) tissue areas.
- They mostly occur randomly but can be linked to genetic conditions like neurofibromatosis type 2.
- A recent case involved a 61-year-old woman whose resected schwannoma showed unusual squamous metaplasia, a finding not previously documented, which could help pathologists identify similar cases in the future.
Article Abstract
Schwannomas are benign peripheral nerve sheath tumors that originate from Schwann cells and characteristically display a biphasic appearance of compact hypercellular and myxoid hypocellular areas, named Antoni A and Antoni B areas, respectively. While most schwannomas arise sporadically, they can be associated with familial tumor syndromes such as neurofibromatosis type 2 and Carney complex. Herein, we report a case of a 61-year-old female who had a schwannoma resected from her upper extremity that later revealed a focus of squamous metaplasia associated with the schwannoma, a finding that has not yet been reported in the literature. This unique finding may aid pathologists in the future when confronted with such an atypical presentation in a schwannoma.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259405 | PMC |
| http://dx.doi.org/10.7759/cureus.62720 | DOI Listing |
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