AI Article Synopsis
- - The study analyzed 17 patients with eosinophilic lung disease, primarily affecting males with an average age of 54; most had a history of uncontrolled asthma and symptoms like persistent dyspnea and cough.
- - Blood tests showed high levels of eosinophils in all patients, with some having significant pulmonary eosinophilia, and imaging revealed diffuse bilateral ground-glass opacities in many cases.
- - The main causes included chronic eosinophilic pneumonia and eosinophilic granulomatosis with polyangiitis, among others; treatment involved systemic corticosteroids, with some patients requiring additional immunosuppressive therapy, and five experienced relapses after stopping corticosteroids.
Article Abstract
In this study, we present findings from an analysis of 17 patients diagnosed with eosinophilic lung disease, with a majority (64.70%) being male. The average age of the patients was 54 ± 13.22 years. A history of uncontrolled asthma was noted in nine cases. The clinical picture was characterized by persistent dyspnea and cough. Blood hypereosinophilia was present in all cases, with a median of 1770 cells/ul. Two patients had a pulmonary eosinophilia greater than 25%. Radiological findings were consistent with diffuse bilateral ground-glass opacities or areas of consolidation in the majority of cases. The main etiologies identified were chronic eosinophilic pneumonia (12 cases), followed by eosinophilic granulomatosis with polyangiitis (3 cases), idiopathic hypereosinophilic syndrome (1 case) and drug-induced hypereosinophilia (1 case). All patients were treated with systemic corticosteroids, with the addition of immunosuppressive therapy necessary in three cases. Notably, five relapses were recorded after corticosteroid therapy was stopped.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11258676 | PMC |
| http://dx.doi.org/10.7759/cureus.62579 | DOI Listing |
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