The study of 430 cerebrospinal fluids resulting from a neurological department showed 67 pathological medical cases according to following tests: intrathecal IgG synthesis and/or restricted heterogeneity with immuno-electrophoresis. We established a biological classification to approach the different etiologies. This classification was used for multiple sclerosis for which various strictly clinical classifications are not always able to diagnose the illness, as we show it for one of them.
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