[Primary laryngeal lymphoma: a case report].

Pan Afr Med J

Université Sidi Mohamed Ben Abdellah, Faculté de Médecine et de Pharmacie de Fès, Centre Hospitalier Universitaire HASSAN II, Fès, Service Oto-Rhino-Laryngologie et Chirurgie Cervico-Faciale, Fès, Maroc.

Published: July 2024

AI Article Synopsis

  • Primary laryngeal lymphoma is a rare type of cancer, making up less than 1% of laryngeal cancers and its treatment varies based on the disease's stage and severity.
  • A case study describes a 64-year-old woman with dysphagia (difficulty swallowing) and a feeling of something stuck in her throat, which led to the discovery of a tumor diagnosed as diffuse large B-cell lymphoma after laryngoscopy and biopsies.
  • The patient underwent chemotherapy followed by radiotherapy and showed significant improvement after 2 years, highlighting the need for tailored diagnostic and treatment strategies due to the rarity and diverse symptoms of this cancer.

Article Abstract

Primary laryngeal lymphoma is rare, accounting for less than 1% of all laryngeal cancers. Treatment depends on the stage and severity of the disease. We here report the exceptional case of a 64-year-old woman, non-smoker, suffering from dysphagia for solids and a foreign body sensation. Laryngoscopy and biopsies revealed polyploid tumor of the left epiglottic fold. The diagnosis of diffuse large B-cell lymphoma was made. The patient underwent chemotherapy followed by radiotherapy, with significant improvement at 2-year follow-up, with no local recurrence. Due to the rarity of this disease and the variety of symptoms, the optimal management strategy for this type of cancer is controversial, requiring a specific diagnostic and therapeutic approach.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11260049PMC
http://dx.doi.org/10.11604/pamj.2024.47.161.41032DOI Listing

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