Sensors are widely used owing to their advantages including excellent sensing performance, user-friendliness, portability, rapid response, high sensitivity, and specificity. Sensor technologies have been expanded rapidly in recent years to offer many applications in medicine, pharmaceuticals, the environment, food safety, and national security. Various nanomaterial-based sensors have been developed for their exciting features, such as a powerful absorption band in the visible region, excellent electrical conductivity, and good mechanical properties. Natural and synthetic coumarin derivatives are attracting attention in the development of functional polymers and polymeric networks for their unique biological, optical, and photochemical properties. They are the most abundant organic molecules in medicine because of their biological and pharmacological impacts. Furthermore, coumarin derivatives can modulate signaling pathways that affect various cellular processes. This review covers the discovery of coumarins and their derivatives, the integration of nanomaterial-based sensors, and recent advances in nanomaterial-based sensing for coumarins. This review also explains how sensors work, their types, their pros and cons, and sensor studies for coumarin detection in recent years.
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http://dx.doi.org/10.1021/acsomega.4c01945 | DOI Listing |
Talanta
January 2025
Department of Electronics and Communication Engineering, Tezpur University, Tezpur, 784028, India. Electronic address:
Detection and analysis of organochlorine pesticides (OCP) residue is getting significant research importance because of their extensive use despite their hazardous effects on the health of people and the ecosystem. Despite the implementation of regulations and bans to safeguard human health and the environment, reports frequently reveal the continued use of these harmful chemicals in quantities exceeding the recommended limits set by regulatory boards. Data on the use of OCP from India, the most populous country, and African countries is not very encouraging.
View Article and Find Full Text PDFACS Sens
January 2025
Institute of Analytical and Bioanalytical Chemistry, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Gastric cancer remains a leading cause of cancer-related mortality, requiring the urgent development of innovative diagnostic tools for early detection. This study presents an integrated infrared spectroscopic electronic nose system, a novel device that combines infrared (IR) spectroscopy and electronic nose (eNose) concepts for analyzing volatile organic compounds (VOCs) in exhaled breath. This system was calibrated using relevant gas mixtures and then tested during a feasibility study involving 26 gastric cancer patients and 32 healthy controls using chemometric analyses to distinguish between exhaled breath profiles.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Department of Chemistry, College of Science, University of Sulaimani, Qliasan St., 46002 Sulaymaniyah, Kurdistan Region, Iraq.
Metal-organic frameworks (MOFs) have emerged as innovative nanozyme mimics, particularly in the area of oxidase catalysis, outperforming traditional MOF-based peroxidase and other nanomaterial-based oxidase systems. This review explores the various advantages that MOFs offer in terms of catalytic activity, low-cost, stability, and structural versatility. With a primary focus on their application in biochemical sensing, MOF-based oxidases have demonstrated remarkable utility, prompting a thorough exploration of their design and modification strategies.
View Article and Find Full Text PDFTalanta
December 2024
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, 144411, India. Electronic address:
The electrochemical biosensor has brought a paradigm shift in the field of sensing due to its fast response and easy operability. The performance of electrochemical sensors can be modified by coupling them with various metal oxides, nanomaterials, and nanocomposites. Hydrogen peroxide is a short-lived reactive oxygen species that plays a crucial role in various physiological and biological processes.
View Article and Find Full Text PDFSensors (Basel)
December 2024
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Food safety is of great concern, and food-borne bacterial infections and diseases are a major crisis for health. Therefore, it is necessary to develop rapid detection techniques for the prevention and recognition of food safety hazards caused by food-borne pathogens. In recent years, the fluorescence assay has become a widely utilized detection method due to its good signal amplification effect, high detection sensitivity, high stability, and short detection time.
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