Capillaroscopy in the daily clinic of the pediatric rheumatologist.

Best Pract Res Clin Rheumatol

Department of Rheumatology, Ghent University Hospital, Belgium; Faculty of Internal Medicine, Ghent University, Ghent, Belgium; Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium.

Published: September 2024

AI Article Synopsis

  • Nailfold capillaroscopy is becoming increasingly important in pediatric rheumatology, aiding in the diagnosis and monitoring of various conditions through a simple, non-invasive procedure.
  • The review highlights essential background on capillaroscopy devices, standardized interpretations, and typical variations observed in healthy children versus those with conditions like Raynaud's phenomenon and systemic diseases.
  • It also identifies gaps in current research, suggesting a need for further studies on the use of nailfold capillaroscopy in pediatric connective tissue diseases.

Article Abstract

In the last decade, nailfold capillaroscopy is finding its way to the daily clinic of (pediatric) rheumatologist. This review will provide the necessary knowledge for the clinician performing this easy and non-invasive examination in children. In the first part, background information on type of capillaroscopy device and standardized (internationally validated) interpretations for the different capillary variables compared to healthy pediatric controls will be provided. The second part focusses on capillary changes that are observed in Raynaud's phenomenon with follow-up recommendations. This part will also cover capillaroscopy findings in juvenile systemic sclerosis, childhood-onset systemic lupus erythematosus, juvenile dermatomyositis and -mixed connective tissue disease, as well as correlations with disease severity. Lastly, a research agenda shows the current gaps we have in knowledge in this niche of nailfold capillaroscopy in pediatric connective tissue diseases.

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Source
http://dx.doi.org/10.1016/j.berh.2024.101978DOI Listing

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