Prostate MRI for the detection of clinically significant prostate cancer: Update and future directions.

Adv Cancer Res

Department of Urology, UT Health San Antonio, San Antonio, TX, United States. Electronic address:

Published: July 2024

AI Article Synopsis

  • The review highlights the growing importance of magnetic resonance imaging (MRI) in detecting clinically significant prostate cancer (csPC) and aims to outline its future role.
  • Recent advancements include improved understanding of MRI-targeted biopsies, the use of biparametric MRI, and changing guidelines around prostate cancer screening and active surveillance.
  • Future directions for MRI in detecting csPC focus on enhancing quality, utilizing artificial intelligence, integrating with PET imaging, and guiding MRI-directed therapies, while emphasizing the need for standardized reporting practices.

Article Abstract

Purpose Of Review: In recent decades, there has been an increasing role for magnetic resonance imaging (MRI) in the detection of clinically significant prostate cancer (csPC). The purpose of this review is to provide an update and outline future directions for the role of MRI in the detection of csPC.

Recent Findings: In diagnosing clinically significant prostate cancer pre-biopsy, advances include our understanding of MRI-targeted biopsy, the role of biparametric MRI (non-contrast) and changing indications, for example the role of MRI in screening for prostate cancer. Furthermore, the role of MRI in identifying csPC is maturing, with emphasis on standardization of MRI reporting in active surveillance (PRECISE), clinical staging (EPE grading, MET-RADS-P) and recurrent disease (PI-RR, PI-FAB). Future directions of prostate MRI in detecting csPC include quality improvement, artificial intelligence and radiomics, positron emission tomography (PET)/MRI and MRI-directed therapy.

Summary: The utility of MRI in detecting csPC has been demonstrated in many clinical scenarios, initially from simply diagnosing csPC pre-biopsy, now to screening, active surveillance, clinical staging, and detection of recurrent disease. Continued efforts should be undertaken not only to emphasize the reporting of prostate MRI quality, but to standardize reporting according to the appropriate clinical setting.

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Source
http://dx.doi.org/10.1016/bs.acr.2024.04.002DOI Listing

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