Stratified epidemic model using a latent marked Hawkes process.

Math Biosci

Department of Mathematics, Imperial College London, London, United Kingdom. Electronic address:

Published: September 2024

We extend the unstructured homogeneously mixing epidemic model introduced by Lamprinakou et al. (2023) to a finite population stratified by age bands. We model the actual unobserved infections using a latent marked Hawkes process and the reported aggregated infections as random quantities driven by the underlying Hawkes process. We apply a Kernel Density Particle Filter (KDPF) to infer the marked counting process, the instantaneous reproduction number for each age group and forecast the epidemic's trajectory in the near future. Taking into account the individual inhomogeneity in age does not increase significantly the computational cost of the proposed inference algorithm compared to the cost of the proposed algorithm for the homogeneously unstructured epidemic model. We demonstrate that considering the individual heterogeneity in age, we can derive the instantaneous reproduction numbers per age group that provide a real-time measurement of interventions and behavioural changes of the associated groups. We illustrate the performance of the proposed inference algorithm on synthetic data sets and COVID-19-reported cases in various local authorities in the UK, and benchmark our model to the unstructured homogeneously mixing epidemic model. Our paper is a "demonstration" of a methodology that might be applied to factors other than age for stratification.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mbs.2024.109260DOI Listing

Publication Analysis

Top Keywords

epidemic model
16
hawkes process
12
latent marked
8
marked hawkes
8
unstructured homogeneously
8
homogeneously mixing
8
mixing epidemic
8
instantaneous reproduction
8
age group
8
cost proposed
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!