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Cognitive Behavioural Therapy to Optimize Post-Operative Recovery (COPE): a randomized controlled feasibility trial in extremity fracture patients.
Pilot Feasibility Stud
January 2025
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Article Synopsis
- The study aimed to assess the feasibility of an online cognitive behavioral therapy (CBT) program for patients recovering from extremity fractures compared to usual care.
- Despite enrolling 94 participants, recruitment showed a "yellow light," indicating some success but needing improvements.
- Compliance with the CBT program was low, as only 60% completed all modules, leading to a "red light," suggesting significant changes are necessary before a larger trial can proceed.
Knowledge of Accredited Social Health Activists in India: a systematic review and meta analysis of evidence drawn from primary studies published between 2005 and 2022.
BMC Health Serv Res
January 2025
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, 21205, USA.
Background: Since the inception of the ASHAs in the year 2005, their work horizons have increased from Reproductive, Maternal, Newborn, Child, and Adolescent health (RMNCH + A), Communicable and Non-Communicable Diseases (CD & NCD) to oral health, ophthalmologic care, and other supportive community level healthcare services. The present literature lacks comprehensive understanding and synthesis of domain-wise knowledge of ASHAs and the factors affecting their knowledge. Therefore, this study aimed to synthesize and collate the relevant evidence to understand the overall knowledge of ASHAs.
View Article and Find Full Text PDFA co-designed health education model to improve outcomes for children with emotional and behavioural difficulties: a study of acceptability, feasibility and impacts.
Arch Dis Child
January 2025
Health Services Research Unit, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Objective: To assess the acceptability and impacts of a co-designed health education model aiming to improve outcomes for children with emotional and behavioural difficulties.
Design: Qualitative focus group study.
Setting: Six primary schools from metropolitan and rural settings in the state of Victoria, Australia.
The role of mitochondrial remodeling in neurodegenerative diseases.
Neurochem Int
January 2025
Department of Environmental and Occupational Health, School of Public Health, Guangdong Medical University, Dongguan, 523808, PR China; Dongguan Key Laboratory of Environmental Medicine, School of Public Health, Guangdong Medical University, Dongguan, 523808, PR China. Electronic address:
Neurodegenerative diseases are a group of diseases that pose a serious threat to human health, such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) and Amyotrophic Lateral Sclerosis (ALS). In recent years, it has been found that mitochondrial remodeling plays an important role in the onset and progression of neurodegenerative diseases. Mitochondrial remodeling refers to the dynamic regulatory process of mitochondrial morphology, number and function, which can affect neuronal cell function and survival by regulating mechanisms such as mitochondrial fusion, division, clearance and biosynthesis.
View Article and Find Full Text PDFDissolved beryllium (< 1 kDa) mobilized as a major element in groundwater in legacy mine waste.
Environ Pollut
January 2025
Applied Geochemistry, Department of Civil, Environmental and Natural Resource Engineering, Luleå University of Technology, Luleå, Sweden.
Research regarding the geochemistry of beryllium (Be) in terrestrial environments is hindered by its high toxicity to humans and the low concentrations normally occurring in the environment. Although Be is considered an immobile element, extremely high dissolved concentrations have been detected in groundwater in the legacy Tailings Storage Facility (TSF) of Smaltjärnen, Sweden. Therefore, a detailed study was conducted to determine physiochemical parameters affecting the speciation of Be in the groundwater.
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