AI Article Synopsis
- * The study identified seven SNPs linked to FER resistance, which explained 4-11% of the trait's variation across 151 tropical maize lines over two seasons.
- * Researchers found significant metabolic pathways related to FER resistance, especially the glyoxylate cycle, highlighting the intricate genetic control of this resistance and its potential for improving disease-resistant maize through marker-assisted selection.
Article Abstract
Unlabelled: Breeding for host resistance is the most efficient and environmentally safe method to curb the spread of fusarium ear rot (FER). However, conventional breeding for resistance to FER is hampered by the complex polygenic nature of this trait, which is highly influenced by environmental conditions. This study aimed to identify genomic regions, single nucleotide polymorphisms (SNPs), and putative candidate genes associated with FER resistance as well as candidate metabolic pathways and pathway genes involved in it. A panel of 151 tropical inbred maize lines were used to assess the genetic architecture of FER resistance over two seasons. During the study period, seven SNPs associated with FER resistance were identified on chromosomes 1, 2, 4, 5, and 9, accounting for 4-11% of the phenotypic variance. These significant markers were annotated into four genes. Seven significant metabolic pathways involved in FER resistance were identified using the Pathway Association Study Tool, the most significant being the superpathway of the glyoxylate cycle. Overall, this study confirmed that resistance to FER is indeed a complex mechanism controlled by several small to medium-effect loci. Our findings may contribute to fast-tracking the efforts to develop disease-resistant maize lines through marker-assisted selection.
Supplementary Information: The online version contains supplementary material available at 10.1007/s10722-023-01793-4.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11252232 | PMC |
| http://dx.doi.org/10.1007/s10722-023-01793-4 | DOI Listing |
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