Early changes in corneal densitometry after FS-LASIK combined with accelerated corneal cross-linking for correction of high myopia.

Int J Ophthalmol

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Shandong Clinical Medicine Research Center, Jinan 250002, Shandong Province, China.

Published: July 2024

AI Article Synopsis

  • The study aimed to assess the impact of combined femtosecond laser-assisted excimer laser keratomileusis (FS-LASIK) and accelerated corneal cross-linking (FS-LASIK Xtra) on corneal densitometry in patients with high myopia.
  • A total of 130 patients who underwent either FS-LASIK or FS-LASIK Xtra were evaluated at multiple points (1, 3, and 6 months post-surgery) for corneal densitometry using advanced imaging techniques.
  • Results showed significant differences in corneal densitometry favoring the FS-LASIK Xtra group during the early months post-surgery, but by 6 months, the densit

Article Abstract

Aim: To observe the effects of femtosecond laser-assisted excimer laser keratomileusis combined with accelerated corneal cross-linking (FS-LASIK Xtra) on corneal densitometry after correcting for high myopia.

Methods: In this prospectively study, 130 patients underwent FS-LASIK or FS-LASIK Xtra for high myopia. Their right eyes were selected for inclusion in the study, of which 65 cases of 65 eyes in the FS-LASIK group, 65 patients with 65 eyes in the FS-LASIK Xtra group. Patients were evaluated for corneal densitometry at 1, 3, and 6mo postoperatively using Pentacam Scheimpflug imaging.

Results: Preoperative differences in corneal densitometry between the FS-LASIK and FS-LASIK Xtra groups in different ranges were not statistically significant (>0.05). Layer-by-layer analysis revealed statistically significant differences in the anterior (120 µm), central, and total layer corneal densitometry between the FS-LASIK and FS-LASIK Xtra groups at 1 and 3mo postoperatively (all <0.05), the FS-LASIK Xtra group is higher than that of the FS-LASIK group. Analysis of different diameter ranges showed statistically significant differences between the FS-LASIK group and the FS-LASIK Xtra group at 1mo postoperatively in the ranges of 0-2, 2-6, and 6-10 mm (both <0.05); At 3mo postoperatively, the FS-LASIK Xtra group is higher than that of the FS-LASIK group in the ranges of 0-2 and 2-6 mm (<0.05). At 6mo postoperatively, there were no statistically significant differences in corneal densitometry between the FS-LASIK group and the FS-LASIK Xtra group in different diameter ranges (all >0.05).

Conclusion: There is an increase in internal corneal densitometry during the early postoperative period after FS-LASIK Xtra for correction of high myopia. However, the densitometry values decreased to the level of conventional FS-LASIK at 6mo after surgery, with the most significant changes observed in the superficial central zone.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11246937PMC
http://dx.doi.org/10.18240/ijo.2024.07.16DOI Listing

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