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Is Plasmalyte beneficial in resuscitation of diabetic ketoacidosis patients? A narrative review. | LitMetric

Is Plasmalyte beneficial in resuscitation of diabetic ketoacidosis patients? A narrative review.

Clin Exp Emerg Med

Department Of Emergency Medicine, Tawam Hospital, Al Ain, Abu Dhabi, United Arab Emirates.

Published: July 2024

AI Article Synopsis

  • * A comprehensive search of studies from PUBMED, EMBASE, and MEDLINE from 2010 to 2023 identified 5 significant randomized controlled trials.
  • * Plasmalyte closely mimics human plasma and helps prevent complications like hyperchloremic metabolic acidosis, but findings on its impact on hospital stay, recovery time, and mortality vary, indicating the need for more research.

Article Abstract

Fluid resuscitation is vital in the resuscitation of diabetic ketoacidosis patients. The purpose of this narrative review is to analyze the role of Plasmalyte in fluid resuscitation of adult diabetic ketoacidosis patients. A thorough search was conducted in PUBMED, EMBASE and MEDLINE. Studies conducted between 1st January 2010 and 31st March 2023 were collected. Of 123 results, 5 pertinent randomized controlled trials were included. The close resemblance of Plasmalyte's electrolyte composition to human plasma and its role in the prevention of hyperchloremic metabolic acidosis are some of its vital benefits in patients with diabetic ketoacidosis. Results on the role of Plasmalyte in length of stay, time to resolution of diabetic ketoacidosis and mortality in diabetic ketoacidosis patients are varied. Hence, further research on these topics is needed.

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Source
http://dx.doi.org/10.15441/ceem.24.209DOI Listing

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