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Correction: PET-CT-guided, symptom-based, patient-initiated surveillance versus clinical follow-up in head neck cancer patients (PETNECK2): study protocol for a multicentre feasibility study and non-inferiority, randomised, phase III trial.
BMC Cancer
July 2024
Institute of Head and Neck Studies and Education (InHANSE), Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Measurement of the Radioactivity of PET/CT-Guided Biopsy Specimen: Is it Helpful to Confirm the Sampling from a Viable Region of the Tumor and the Nature of the Lesion?
Indian J Nucl Med
July 2022
Department of Nuclear Medicine and PET/CT, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Article Synopsis
- The study aimed to measure radioactivity in biopsy tissue specimens using PET/CT imaging to ensure viable tumor sampling and predict the lesion's nature.
- A total of 49 patients underwent PET/CT-guided biopsies, with all samples showing radioactivity; the mean counting-factor (CF) was significantly higher for malignant lesions compared to benign ones (21.45 vs. 10.76 counts/mCi.mm).
- The findings indicate that measuring tissue radioactivity can confirm viable sampling and reduce errors in diagnosing lesions, thus providing valuable insights before histopathology.
Dual-tracer PET/CT-targeted, mpMRI-targeted, systematic biopsy, and combined biopsy for the diagnosis of prostate cancer: a pilot study.
Eur J Nucl Med Mol Imaging
July 2022
Department of Urology, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People's Republic of China.
Purpose: Growing evidence proved the efficacy of multi-parametric MRI (mpMRI) and prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT)-guided targeted biopsy (TB) in prostate cancer (PCa) diagnosis, but there is no direct comparison between mpMRI-TB and PSMA PET/CT-TB. Gastrin-releasing peptide receptor (GRPR) is highly expressed in PCa, which can compensate for the unstable expression of PSMA in PCa. Therefore, we designed a study to compare the efficiency of mpMRI-TB, dual-tracer (GRPR and PSMA) PET/CT-TB, systematic biopsy, and combined biopsy for the diagnosis of prostate cancer.
View Article and Find Full Text PDFKRAS mutation effects on the 2-[18F]FDG PET uptake of colorectal adenocarcinoma metastases in the liver.
EJNMMI Res
November 2020
Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Background: Deriving individual tumor genomic characteristics from patient imaging analysis is desirable. We explore the predictive value of 2-[18F]FDG uptake with regard to the KRAS mutational status of colorectal adenocarcinoma liver metastases (CLM).
Methods: 2-[18F]FDG PET/CT images, surgical pathology and molecular diagnostic reports of 37 patients who underwent PET/CT-guided biopsy of CLM were reviewed under an IRB-approved retrospective research protocol.
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