Maternal and prenatal exposure to organochlorine pesticides (OCP), arsenic (As), and fluoride (F) is a critical public health concern. The present study assessed serum OCP residues and urinary As and F levels in mother and newborn pairs who are residents of rural areas of Durango State, Mexico, from August 2018 to February 2019. Levels of OCP, As, and F were measured in serum and urine samples by Gas chromatography - Tandem mass spectrometry (GC - MS/MS), Hydride generation - Atomic fluorescent spectrometry (HG-AFS, and ion-selective electron analysis (ISE), respectively, in 60 binomial mothers - newborns. Dieldrin, endrin aldehyde, and endosulfan-II were significantly higher in newborns than in mothers ( ˂0.05). Meanwhile, no significant differences were observed for As and F concentrations between mother - newborn pairs. Differences were observed in ∑Dienes and ∑DDTs comparing newborns with normal and low birth weights and a positive relationship in ƩDienes, ƩChlordanes, and ƩDDTs between mother and newborn pairs ( ˂ 0.05). These findings highlight the importance of extensive research regarding the influence of pollution.
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http://dx.doi.org/10.1080/09603123.2024.2379991 | DOI Listing |
Front Mol Biosci
December 2024
Metabolomics Section, Department of Clinical Genomics, Center for Genomics Medicine, King Faisal Specialist Hospital and Research Centre (KFSHRC), Riyadh, Saudi Arabia.
Introduction: Gestational Diabetes Mellitus (GDM) is a metabolic disorder marked by Q10 hyperglycemia that can negatively affect both mothers and newborns. The increasing prevalence of GDM and the limitations associated with the standard diagnostic test highlight the urgent need for early screening strategies that promote timely interventions.
Methods: This study aims to investigate the metabolic profile associated with GDM through an untargeted metabolomic analysis using mass spectrometry (MS)- based omics.
BMC Pediatr
January 2025
Department of Pediatrics and Neonatal Nursing, School of Nursing and Midwifery, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.
Background: Community-Based Newborn Care [CBNC] program aims to improve the health of the newborns. Despite management improvements, many young infants with serious bacterial infections [PSBI] in resource-limited settings are not receiving recommended inpatient treatment due to accessibility, affordability, or family acceptance issues. Therefore, this study aimed to assess the level of CBNC utilization and associated factors among women who delivered recently their newborns in Nekemte city, West Oromia, Ethiopia.
View Article and Find Full Text PDFCardiol Young
January 2025
Department of Community Medicine, F.H. Medical College, Agra, Uttar Pradesh, India.
Infants of diabetic mothers are neonates born to a woman who had periodic hyperglycaemia during pregnancy. Consequently, infants of diabetic mothers are at higher risks of illness besides morbidity and mortality due to teratogenic effects on the fetal cardiovascular system, causing most frequent CHDs. The primary purpose of this review is to present, on this topic, a better-comprehended review covering pertinent material and data to be informed of severe risks to a newborn's cardiac system and function.
View Article and Find Full Text PDFArch Dis Child Fetal Neonatal Ed
January 2025
Paediatrics, Mount Sinai Hospital PLM, Toronto, Ontario, Canada
Objective: Size at birth is a key indicator of in utero growth. Our objective was to generate sex-specific percentiles for birth weight and head circumference in neonates born between 22 and 29 weeks gestation from pregnancies without hypertension or diabetes and assess differences between vaginal and caesarean births and between singletons and twins.
Methods: We used data from 12 countries participating in the International Network for Evaluating Outcomes in Neonates database from 2007 to 2021.
Andes Pediatr
October 2024
Departamento de Neuropediatría, Hospital Fundación Alcorcón, Madrid, España.
Unlabelled: Congenital myotonic dystrophy type 1 (DM1) is a rare entity that can pose a diagnostic challenge, especially if other processes such as prematurity coexist.
Objective: to describe the typical presentation of congenital DM1 and thus increase diagnostic suspicion.
Clinical Case: A 29-week preterm female newborn who required non-invasive mechanical ventilation until 41 weeks postmenstrual age; she presented with apnea requiring manual ventilation with a self-inflating bag and cardiac massage.
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