AI Article Synopsis
- * There is a need for deeper research into the biological mechanisms of COPD to find new treatment options.
- * Recent studies highlight the important roles of various noncoding RNAs, like miRNAs and lncRNAs, in the development of COPD, suggesting that RNA-based therapies could be a promising approach for management.
Article Abstract
Chronic obstructive pulmonary disease (COPD) is the most prevalent chronic respiratory disorder that is becoming the leading cause of morbidity and mortality on a global scale. There is an unmet need to investigate the underlying pathophysiological mechanisms and unlock novel therapeutic avenues for COPD. Recent research has shed light on the significant roles played by diverse noncoding RNAs (ncRNAs), including microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), in orchestrating the development and progression of COPD. This review provides an overview of the regulatory roles of ncRNAs in COPD, elucidating their underlying mechanisms, and illuminating the potential prospects of RNA-based therapeutics in the management of COPD.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11254503 | PMC |
| http://dx.doi.org/10.1016/j.ncrna.2024.06.005 | DOI Listing |
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