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Rapid Screening of 60 Types of Natural Toxins in Whole Blood by UPLC-Q/Orbitrap HRMS.

Fa Yi Xue Za Zhi

December 2024

Shanghai Key Laboratory of Crime Scene Evidence, Institute of Forensic Science, Shanghai Public Security Bureau, Shanghai 200083, China.

Objectives: To establish a rapid screening method for 60 types of natural toxins in whole blood by ultra-high performance liquid chromatography-quadrupole/electrostatic field orbitrap high resolution mass spectrometry (UPLC-Q/Orbitrap HRMS).

Methods: The chromatographic and mass spectrometric information of 60 standard samples of natural toxins were analyzed and recorded, and a screening database was built. Whole blood was pretreated by protein precipitation method combined with ultrasonic-assisted dispersion, and then a Hypersil GOLD C column was used with 5 mmol/L ammonium formate aqueous solution (containing 0.

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Cellular and Histopathological Characteristics of Ultrasonically Underdiagnosed 3/4a Thyroid Nodules.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao

February 2025

Department of Pathology,Quanzhou, Fujian 362000,China.

Objective To analyze the cellular and histopathological characteristics of underdiagnosed thyroid nodules of Chinese thyroid imaging reporting and data system(C-TIRADS) categories 3 and 4a,thus improving the understanding of these lesions. Methods The data of ultrasound and fine needle aspiration cytology were collected from 683 nodules diagnosed based on pathological evidence in 549 patients undergoing thyroid surgery.The cellular and histopathological characteristics of C-TIRADS 3 and 4a nodules were analyzed.

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Geometric a priori informed bent-ray tracing for accelerated sound speed imaging in ultrasound computed tomography.

Ultrasonics

March 2025

School of Information Science and Technology, ShanghaiTech University, Shanghai, 201210, China; Shanghai Engineering Research Center of Intelligent Vision and Imaging, ShanghaiTech University, Shanghai, 201210, China; Key Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address:

Bent-ray tracing ultrasound computed tomography (USCT) is a promising technique for breast cancer screening which quantitatively provides speed-of-sound (SOS) distribution in human breasts. In this modality, SOS images are reconstructed with an iterative process to match the measured time-of-flights and the ones predicted by Eikonal equation solved with the fast marching method (FMM). The Eikonal equation is meant to be applied in SOS heterogeneous media and its evaluation with FMM is an computational expensive process.

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Cemental tear, characterized by the separation of the cementum from the root surface of a tooth, is commonly observed in patients with localized periodontitis, particularly those with a complex medical history resulting in significant periodontal damage. This condition complicates both diagnosis and treatment, and cone beam computed tomography (CBCT) is a valuable tool for assessing the extent of damage and guiding treatment decisions. This report presents 3 clinical cases of cemental tear.

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Background And Aim: Pulmonary thromboembolism (PTE) is a common cause of cardiovascular death worldwide. Due to its nonspecific clinical symptoms, PTE is easy to be missed or misdiagnosed. Pulmonary transit time (PTT) is a noninvasive cardiopulmonary hemodynamic index, which is the time required for a blood sample to pass through pulmonary circulation.

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