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Primary Classic Penile Kaposi's Sarcoma in a Middle Age Circumcised HIV-Negative Patient: Presentation of an Unusual Case. | LitMetric

AI Article Synopsis

  • * A 37-year-old heterosexual man presented with a painless penile lesion that lasted three months, and he tested negative for HIV but positive for HHV-8.
  • * Histopathological study of the lesion showed atypical spindle cells and a lot of plasma cells, leading to a diagnosis of HIV-negative Kaposi sarcoma, despite its rarity in penile cases.

Article Abstract

Kaposi's sarcoma should be considered in the differential diagnosis in young patients with penile lesions and no risk factors. A 37-year-old heterosexual man with no other medical history applied presented with a non-itchy and painless penile lesion, for three months. The HIV 1-2 serology was negative via ELISA test. Histopathological analysis of the lesion revealed a tumor composed of atypical spindle cells, below a partially ulcerated surface. There was also an abundance of plasma cells admixed within the neoplastic cells. The patient was diagnosed as HIV-negative, HHV-8 positive Kaposi sarcoma. Although penile Kaposi sarcoma is extremely rare, classical Kaposi sarcoma should be considered in the differential diagnosis of penile lesions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249993PMC
http://dx.doi.org/10.14744/SEMB.2023.46034DOI Listing

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