Amplitude death has the potential to suppress unwanted oscillations in various engineering applications. However, in some engineering applications, such as dc microgrids, airfoil systems, and thermoacoustic systems, oscillation frequency is highly susceptible to external influences, leading to considerable variations. To maintain amplitude death amidst these frequency variations, we propose a design procedure that is robust against frequency variation for inducing amplitude death in delay-coupled oscillators. We first analytically derive the oscillator frequency band in which amplitude death can occur. The frequency bandwidth is maximized when the coupling strength is inversely proportional to the connection delay. Furthermore, our analysis reveals that the oscillator frequency band is influenced by the minimum eigenvalue of the normalized adjacency matrix (i.e., network topology) and that bipartite networks exhibit limited robustness to frequency variations. Our design procedure maintains the stability of amplitude death even under substantial frequency variations and is applicable to various network topologies. Numerical simulations confirm the validity of the proposed design.
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http://dx.doi.org/10.1103/PhysRevE.109.064213 | DOI Listing |
J Pharmacol Sci
February 2025
Department of Pharmacology, Showa University Graduate School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan; Pharmacological Research Center, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.
Diabetic retinopathy (DR) is the leading cause of blindness among working-age adults, and inflammation and oxidative stress contribute to DR development. However, no effective treatments are currently approved for DR. Therefore, this study aimed to investigate the effects of SMTP-44D-a Stachybotrys microspora-derived compound with anti-inflammatory and antioxidant properties-on DR in in vivo and in vitro models.
View Article and Find Full Text PDFForensic Sci Int
January 2025
Department of Forensic Medicine, Soochow University, Ganjiang East Road, Suzhou, Jiangsu, China. Electronic address:
Necrophagous blow flies are a commonly used forensic tool to estimate the minimum postmortem interval (PMI), where researchers collect development data under constant temperature regimes and construct models to estimate PMI. However, the ambient temperatures of real death scenes are often fluctuant, which limits the reliability of data obtained under constant temperature regimes. Here we investigate the possible differences in the development of Chrysomya megacephala (Fabricius, 1794) (Diptera: Calliphoridae), an important species in forensic entomology.
View Article and Find Full Text PDFAm J Cardiovasc Drugs
January 2025
Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai, China.
Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) have demonstrated promising effects in lowering cardiovascular incidents among patients with acute coronary syndrome. However, their influence on early platelet reactivity after primary percutaneous coronary intervention (PPCI) remains unclear.
Objectives: This research sought to investigate the effects of entirely human anti-PCSK9 antibodies on platelet function as measured by thrombelastography and 12-month postoperative results in patients receiving PPCI and treated with ticagrelor-based dual antiplatelet therapy.
Adv Mater
January 2025
State Key Laboratory of Fine Chemicals, Department of Pharmacy, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Phytochlorins, a class of plant-derived tetrapyrroles, show great potential as sonosensitizers in sonodynamic therapy (SDT). The development of new phytochlorin-based sonosensitizers has significantly improved SDT, yet the absence of specialized sonodynamic systems limits their clinical translation. Herein, a dedicated ultrasound system along with a detailed step-by-step sonodynamic process from in vitro to in vivo is developed to activate phytochlorin-based sonosensitizers.
View Article and Find Full Text PDFEarly Hum Dev
January 2025
Division of Neonatology, Department of Maternal, Fetus and Perinatal Center, Saitama Children's Medical Center, Saitama, Japan.
Background: Hypoxic-ischemic encephalopathy (HIE) is still associated with death and sequelae including cerebral palsy and intellectual disability despite induced hypothermia. Biomarkers, as early predictive indicators of adverse outcomes, are lacking.
Aims: To investigate whether post-rewarming cerebrospinal fluid (CSF)-neuro-specific enolase (NSE) levels after hypothermia are associated with neurodevelopmental outcomes at age six years, alone or when combined with amplitude-integrated electroencephalography (aEEG) and brain magnetic resonance imaging (MRI), as neuroimaging and neurophysiological indicators, respectively.
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