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Recurrent Corneal Erosion Induced by 1% 5-Fluorouracil Solution.
Cureus
November 2024
Ophthalmology, Hiroshima University, Hiroshima, JPN.
Cytotoxic anticancer drug solution eye drops can hinder the cell division of corneal basal cell division and corneal limbal epithelial stem cell migration. We discuss a case involving recurrent corneal epithelial erosions induced by 1% 5-fluorouracil (5-FU) solution eye drops. A 68-year-old male with conjunctival papilloma on his left eye underwent recurrences three times and additional tumor excision.
View Article and Find Full Text PDFConjunctivo-rhinostomy with Métaireau tube implant: Outcomes and complications.
Arch Soc Esp Oftalmol (Engl Ed)
December 2024
Servicio de Oftalmología, Hospital Universitario La Paz, Madrid, Spain.
Purpose: To communicate the results and complications in a series of 17 proximal lacrimal pathway obstructions (PLPO) operated by conjunctivo-rhinostomy (CR) with Métaireau tube implantation.
Methods: Retrospective descriptive study including 16 patients (17 PLPO) operated with CR between April 2010 and June 2017. Surgeries were performed under general anesthesia.
Systemic Treatment with the Janus Kinase Inhibitor Baricitinib in Ocular Chronic Graft-versus-Host Disease.
Ophthalmol Sci
September 2024
Ophthalmology Consult Services Section, National Eye Institute, NIH, Bethesda, Maryland.
Objective: To investigate the effects of oral baricitinib on ocular surface disease (OSD) in patients with chronic graft-versus-host disease (cGVHD).
Design: Prospective phase 1 to 2 single institution trial.
Subjects: Eighteen patients with ocular graft-versus-host-disease (oGVHD) and systemic steroid-refractory cGVHD.
Dupilumab-Associated Bilateral Conjunctival Papillomas and Corneal Perforation.
Cornea
November 2024
Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
Purpose: We report a unique case of significant human papillomavirus-associated conjunctival papillomas and severe corneal ulceration leading to corneal perforation in a patient treated with dupilumab for atopic dermatitis.
Methods: This study is a case report and literature review of severe corneal side effects related to dupilumab.
Results: A 27-year-old man with severe atopic dermatitis and no ocular history was administered dupilumab 300 mg via subcutaneous injections every 2 weeks with an excellent response.
Can high-resolution optical coherence tomography provide an optical biopsy for ocular surface lesions?
Can J Ophthalmol
August 2024
Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL. Electronic address:
Article Synopsis
- High-resolution optical coherence tomography (HR-OCT) helps doctors see detailed pictures of eye surface problems, making it easier to diagnose and treat them.
- It can show different types of issues like tumors and helps tell them apart, even when they look similar.
- HR-OCT is important for doctors because it allows them to check how well treatments are working and keep an eye on any tumors that might grow back.
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