AI Article Synopsis
- Nature has inspired the creation of biomimetic membrane sensors that utilize biological molecules like proteins and lipids for sensing tasks.
- The review discusses recent advancements in two types of biomembrane sensors: those using lipid vesicles for bulk applications and supported lipid bilayers for planar applications.
- It emphasizes the key components and design principles needed for these sensors, along with their diverse applications across various fields, showcasing the potential enhancement of biosensor platforms by leveraging nature's biomembrane capabilities.
Article Abstract
Nature has inspired the development of biomimetic membrane sensors in which the functionalities of biological molecules, such as proteins and lipids, are harnessed for sensing applications. This review provides an overview of the recent developments for biomembrane sensors compatible with either bulk or planar sensing applications, namely using lipid vesicles or supported lipid bilayers, respectively. We first describe the individual components required for these sensing platforms and the design principles that are considered when constructing them, and we segue into recent applications being implemented across multiple fields. Our goal for this review is to illustrate the versatility of nature's biomembrane toolbox and simultaneously highlight how biosensor platforms can be enhanced by harnessing it.
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| http://dx.doi.org/10.1146/annurev-anchem-061622-042618 | DOI Listing |
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