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Recovery rate after acute acoustic trauma: a case series and meta-analysis. | LitMetric

Recovery rate after acute acoustic trauma: a case series and meta-analysis.

Eur Arch Otorhinolaryngol

Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.

Published: December 2024

AI Article Synopsis

  • Steroids are a key treatment for acute acoustic trauma (AAT), but the overall recovery rate is not well defined.
  • A study analyzed cases from 2012 to 2022, combining original case data with a systematic review of existing literature to evaluate treatment outcomes.
  • Results showed about 70% of ears experienced some recovery with steroids, while around 30% achieved full recovery if treatment began within the first two weeks post-injury.

Article Abstract

Objective: Steroids given systemically, locally, or both are the mainstay of treatment for acute acoustic trauma (AAT). The overall recovery rate (full, partial, and none) is undetermined.

Study Design: Original case series and systematic literature review.

Setting: Case series of a tertiary referral center and a systematic literature review.

Methods: Cases of AAT between 2012 and 2022 were retrospectively analyzed for demographics, acoustic trauma characteristics, treatment modality and delay and prognosis. This case series was added to the series identified by a systematic literature review. This review included "Medline" via "PubMed", "EMBASE", and "Google scholar". All series were pooled for meta-analysis defining prognosis following steroidal treatment for AAT patients.

Results: The pooled analyses included 662 ears, out of which 250 underwent complete recovery of hearing (overall proportion = 0.2809, 95%confidence interval [CI] = 0.1611-0.4178). Any recovery was recorded for 477 ears (overall proportion = 0.7185, 95% CI = 0.5671-0.8493) and no recovery was documented for 185 ears (overall proportion = 0.2815, 95% CI = 0.1507-0.4329).

Conclusion: The rate of overall recovery for AAT is around 70%, and around 30% for full recovery when steroids are initiated within the first 2 weeks following the insult.

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Source
http://dx.doi.org/10.1007/s00405-024-08847-yDOI Listing

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