Introduction: Medical cannabis treatment for autistic children has recently become popular, and studies have focused on examining the treatment's effects on children's symptom presentation, reported side effects, and dropout rates. However, no previous study has investigated the factors influencing adherence and dropout rates in cannabis treatment.
Method: This explanatory sequential mixed-methods study explored these factors by examining the characteristics of 87 autistic children and their families and deepening parents' perspectives and experiences of the 6-month CBD-rich cannabis treatment's benefits and barriers.
Results: We found this treatment to have a high (75%) adherence rate, relatively mild side effects, and substantial reported benefits for the children and families. However, this treatment was not free of barriers; the intake regime, some side effects, and in some cases, unrealistic parental expectations made adherence difficult for some families.
Conclusion: Our results highlight the importance of providing professional guidance and knowledge to parents of autistic children, enhancing their understanding of the impact of CBD-rich cannabis treatment on their children and expected related challenges, and coordinating realistic treatment expectations. We hope that addressing these important aspects will influence parents' ability to adhere to and enjoy the benefits of cannabis treatment for their autistic children.
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http://dx.doi.org/10.1159/000538901 | DOI Listing |
Nutrients
January 2025
Department of Pediatrics, Buzzi Children's Hospital, 20154 Milan, Italy.
Background: The metabolism of plasma amino acid (AA) in children with autism spectrum disorder (ASD) has been extensively investigated, yielding inconclusive results. This study aims to characterize the metabolic alterations in AA profiles among early-diagnosed children with ASD and compare the findings with those from non-ASD children.
Methods: We analyzed plasma AA profiles, measured by ion exchange chromatography, from 1242 ASD children (median age = 4 years; 81% male).
J Clin Med
January 2025
Owerko Centre at the Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB T2N 1N4, Canada.
: Our understanding of the transdiagnostic factors that influence health-related quality of life (HRQOL) in individuals with neurodivergent conditions is very sparse and highly siloed by diagnosis labels. Research on transdiagnostic predictors of HRQOL across neurodevelopmental conditions is needed to enable care models that address shared needs of neurodivergent individuals beyond diagnostic boundaries. Our objective was to identify transdiagnostic factors associated with HRQOL in children with autism, epilepsy, or comorbid autism/epilepsy.
View Article and Find Full Text PDFChildren (Basel)
January 2025
Department of Biological and Environmental Science and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.
Background/objectives: The main objective of this manuscript is to evaluate the effects of training, music, and movement intervention on motor functions, social engagement, and behaviors in autistic children.
Methods: Twenty-one children with a diagnosis of mild autism spectrum disorder (ASD), with an age range of 5-to-13 years, were divided into two groups: the experimental group ( = 10) and the control group ( = 11). All participants were examined before (T0) and after the intervention (T1) to evaluate their motor functions (Bruininks-Oseretsky Motor Performance Test (BOT-2)), maladaptive behavior (RCS (Response to Challenge Scale)), and enjoyment and engagement (PACES (Physical Activity Enjoyment Scale)).
Children (Basel)
December 2024
Department of Medical-Surgical Sciences and Biotechnologies, University of Rome La Sapienza, 04100 Latina, Italy.
Background/objectives: Children on the autism spectrum experience more oral hygiene issues than peers, and tooth-brushing behavior seems particularly challenging for them since it includes diverse skills and collaboration. In this study, the efficacy is explored of a behavioral intervention mediated by staff and parents in teaching self-brushing teeth in eight autistic children. First, we wanted to examine whether the intervention improved self-brushing teeth skills in a short-term period.
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Maternity & Pediatrics Nursing Department, Faculty of Nursing, Princess Nourah bint Abdulrahman University, Riyadh 11564, Saudi Arabia.
: Mothers of children with autism spectrum disorder (ASD) often experience significant stress, which can adversely affect their quality of life (QoL) and increase their reliance on social support. This study aimed to explore the relationship between social support and QoL among mothers of ASD children and identify associated factors. : A cross-sectional study was conducted from December 2022 to March 2023, involving 218 mothers of ASD children in Saudi Arabia.
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