Background: To report real-world outcomes of patients with primary Reghmatogenous Retinal Detachment (RRD) treated with Pneumatic Retinopexy (PnR) according to the indications of the Pneumatic Retinopexy versus Vitrectomy for management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial (PIVOT) trial.
Methods: Multicenter, retrospective study. Patients treated with PnR for RRD between 2021 and 2023 and a follow-up of at least 6 months were included. Single-procedure anatomical success, final anatomical success, complications, causes of failures, best corrected visual acuity (BCVA) after surgery, and the vision-related quality of life using the 25-Item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) were reported.
Results: A total of 76 eyes of 76 patients were included. Mean age was 60 ± 8.1 years. Primary anatomic reattachment was achieved by 84.3% of patients and final anatomical reattachment after pars plana vitrectomy was obtained in 100% of patients. BCVA improved from 0.32 (20/40) to 0.04 (20/20) logMar (p < 0.001) at 6 months. The main cause of failure was related to the presence of additional (likely missed) retinal breaks (66.6% of cases). Also, primary PnR failure was more frequent in eyes of patients with older age, macular involvement, worse baseline BCVA, greater extent of the RRD, and increased duration from diagnosis to treatment. Overall, the mean NEI-VFQ 25 composite score was 93.9% ± 6.4 at 6 months.
Conclusions: The criteria of the PIVOT trial can be applied to real-world scenarios in the decision-making process for the treatment of primary RRD, with excellent anatomical and functional outcomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11251132 | PMC |
| http://dx.doi.org/10.1186/s12886-024-03559-7 | DOI Listing |
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Article Synopsis
- The study aimed to analyze the treatment patterns and outcomes of pneumatic retinopexy (PnR) in patients with rhegmatogenous retinal detachments (RRD) utilizing data from the IRIS® Registry over the years 2013-2022.
- Results showed that the overall single-operation success (SOS) rate for PnR was 59.82%, with specific complications noted, such as vitreous hemorrhage in 9.1% of cases, and poorer visual acuity outcomes for eyes that failed the procedure.
- The findings concluded that, while PnR is widely used, its SOS rate is lower than previously reported, and phakic eyes had better outcomes compared to pseud
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