AI Article Synopsis
Article Abstract
Purpose: Physical activity research among patients with metastatic breast cancer (MBC) is limited. This study examined the feasibility and potential benefits of Fit2ThriveMB, a tailored mHealth intervention.
Methods: Insufficiently active individuals with MBC (n = 49) were randomized 1:1 to Fit2ThriveMB (Fit2ThriveMB app, Fitbit, and weekly coaching calls) or Healthy Lifestyle attention control (Cancer.Net app and weekly calls) for 12 weeks. Fit2ThriveMB aimed to increase daily steps via an algorithm tailored to daily symptom rating and step goal attainment. The primary outcome was feasibility defined as ≥ 80% completion rate. Secondary feasibility metrics included meeting daily step goal and wearing the Fitbit ≥ 70% of study days, fidelity, adherence to intervention features and safety. Secondary outcomes included physical activity, sedentary time, patient reported outcomes (PROs), health-related quality of life (QOL) and social cognitive theory constructs. A subsample (n = 25) completed functional performance tests via video conferencing.
Results: The completion rate was 98% (n = 1 died). No related adverse events were reported. Fit2ThriveMB participants (n = 24) wore the Fitbit 92.7%, met their step goal 53.1%, set a step goal 84.6% and used the app 94.1% of 84 study days. Intent-to-treat analyses indicated trends toward improvements in activity, QOL, and some PROs, social cognitive theory constructs, and functional performance tests favoring the Fit2ThriveMB group. Significant effects favoring Fit2ThriveMB were observed for self-efficacy and goal-setting. However, some PROs and functional performance improvements favored the control group (p-values > 0.05).
Conclusions: Fit2ThriveMB is feasible and safe for patients with MBC and warrants further evaluation in randomized controlled trials with larger sample sizes. Registration Clinicaltrials.gov NCT04129346, https://clinicaltrials.gov/ct2/show/NCT04129346.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10549-024-07432-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Acute effect of exercise on appetite-related factors in males with obesity: A pilot study.
Physiol Rep
December 2024
Department of Exercise Physiology, University of Guilan, Guilan, Iran.
To investigate the role of appetite-related factors, including interleukin 6 (IL-6), irisin, interleukin 7 (IL-7), neuropeptide Y (NPY), and leptin, on appetite perception in males with obesity. Eleven males (BMI 35.3 ± 4.
View Article and Find Full Text PDFPlasma and salivary hormone responses to a 30-min exercise stress test in young, healthy, physically active females.
Physiol Rep
December 2024
SHAPE Research Centre, Department of Sport Science, Nottingham Trent University, Nottingham, UK.
Overreaching, a consequence of intensified training, is used by athletes to enhance performance. A blunted hormonal response to a 30-min interval exercise stress test (55/80) has been shown in males after intensified training, highlighting cortisol and testosterone as potential biomarkers of overreaching. Despite accounting for ~50% of the population, studies into hormonal responses to exercise in females are lacking.
View Article and Find Full Text PDFThe effect of silicon supplementation and drought stress on the deposition of callose and chemical components in the cell walls of the Brassica napus roots.
BMC Plant Biol
December 2024
The Franciszek Górski Institute of Plant Physiology, Polish Academy of Sciences, Niezapominajek 21, Kraków, 30-239, Poland.
Background: Silicon has an important role in regulating water management in plants. It is deposited in cell walls and creates a mechanical barrier against external factors. The aim of this study was to determine the role of silicon supplementation in the synthesis and distribution of callose in oilseed rape roots and to characterize the modifications of cell wall structure of these organs after exposure to drought stress.
View Article and Find Full Text PDFThe segmental-based approach during anatomy coursework presents better results than the systems-based approach.
BMC Med Educ
December 2024
Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia, Brasil.
Traditionally, there are two pedagogical approaches to teaching human anatomy. The first is the systems-based approach (study of body systems - bones, muscles, organs - separately) gross anatomy courses and the second is the segmental-based approach (study of body segments - upper and lower limbs and trunk - separately); both are highly recommended. However, to the best of our knowledge, less is known about academic performance comparing the two approaches.
View Article and Find Full Text PDFAssociations of tobacco use, physical activity and diet with hypertension in the city of Kandahar, Afghanistan: a community-based cross-sectional study.
BMC Res Notes
December 2024
Department of Internal Medicine, Faculty of Medicine, Kandahar University, Kandahar, Afghanistan.
Objective: Hypertension exerts a substantial financial burden on individuals, families, communities, and the health system of a country. The current study aimed to describe the association of hypertension with its main risk factors in the Afghan population living in Kandahar city.
Results: The prevalence of tobacco smoking, naswar use, physical activity and a healthy diet was 22%, 55%, 63.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!