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Case Report: Disseminated Tuberculosis After Kidney Transplantation. | LitMetric

Case Report: Disseminated Tuberculosis After Kidney Transplantation.

Am J Trop Med Hyg

Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Published: September 2024

AI Article Synopsis

  • Tuberculosis (TB) poses a serious risk for solid organ transplant (SOT) recipients, particularly affecting kidney transplant patients, though there’s limited data on this.
  • In immunocompromised individuals, TB can present in unusual ways, so healthcare providers need to be vigilant, especially if the patient has lived in areas where TB is common.
  • A notable case describes a 54-year-old Filipino woman who developed severe TB complications, underscoring the importance of prevention, diagnosis, and treatment in managing this potentially deadly and curable disease.

Article Abstract

Tuberculosis (TB) can cause significant morbidity and mortality among solid organ transplant (SOT) recipients, including disseminated disease. Most TB cases after SOT occur in kidney transplant recipients, although data about TB in this population are sparse. Tuberculosis may present atypically in immunocompromised patients, underscoring why physicians must maintain high clinical suspicion when pertinent epidemiological risk factors are present, including birth or former residence in a country with endemic TB. We describe a unique case of disseminated TB in a 54-year-old Filipino woman who developed central nervous system tuberculoma, Pott's disease, chorioretinitis, and a perinephric fluid collection after kidney transplantation. Despite being a preventable and curable disease, TB remains a relevant and challenging infection with complex diagnostic and treatment guidelines.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11376149PMC
http://dx.doi.org/10.4269/ajtmh.23-0358DOI Listing

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