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Preoperatively predicting failure to achieve the minimum clinically important difference and the substantial clinical benefit in patient-reported outcome measures for total hip arthroplasty patients using machine learning.
BMC Musculoskelet Disord
February 2025
Florida Orthopaedic Institute, Gainesville, FL, USA.
Background: Attention to the collection of patient-reported outcomes measures (PROMs) associated with total hip arthroplasty (THA) is growing. The aim of this study was to preoperatively predict failure to achieve the minimal clinically important difference (MCID) and substantial clinical benefit (SCB) between pre- and postoperative PROMs. In addition, we sought to identify factors predictive of failure to achieve MCID and SCB in patients undergoing a THA.
View Article and Find Full Text PDFThe impact of inadequate disclosure and patient recall on the consent process in neurosurgery: A systematic literature review.
Surgeon
February 2025
Royal College of Surgeons in Ireland, Department of General Practice, MSc in Health Care Ethics and Law, United Kingdom.
Article Synopsis
- The informed consent process in neurosurgery aims to respect patient autonomy but often suffers from communication gaps between patients and surgeons.
- A systematic review analyzed 28 studies to evaluate how different consent methods impact neurosurgical practice, revealing risks of legal issues due to inadequate information sharing.
- The authors concluded that improving communication and using diverse consent strategies can enhance patient understanding, reduce litigation risks, and promote better collaborative decision-making in neurosurgery.
Collaborative Outcomes Study on Health and Functioning During Infection Times (COH-FIT): Global and Risk-Group Stratified Course of Well-Being and Mental Health During the COVID-19 Pandemic in Adolescents.
J Am Acad Child Adolesc Psychiatry
November 2024
Charité Universitätsmedizin Berlin, Berlin, Germany; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, USA; Zucker Hillside Hospital, Northwell Health, and the Feinstein Institutes for Medical Research, New York. Electronic address:
Objective: To identify the COVID-19 pandemic impact on well-being/mental health, coping strategies, and risk factors in adolescents worldwide.
Method: This study was based on an anonymous online multi-national/multi-language survey in the general population (representative/weighted non-representative samples, 14-17 years of age), measuring change in well-being (World Health Organization-Five Well-Being Index [WHO-5]/range = 0-100) and psychopathology (validated composite P-score/range = 0-100), WHO-5 <50 and <29, pre- vs during COVID-19 pandemic (April 26, 2020-June 26, 2022). Coping strategies and 9 a priori- defined individual/cumulative risk factors were measured.
The hippocampal CA2 region discriminates social threat from social safety.
Nat Neurosci
November 2024
Zuckerman Mind Brain Behavior Institute, Columbia University, New York City, NY, USA.
The dorsal cornu ammonis 2 (dCA2) region of the hippocampus enables the discrimination of novel from familiar conspecifics. However, the neural bases for more complex social-spatial episodic memories are unknown. Here we report that the spatial and social contents of an aversive social experience require distinct hippocampal regions.
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