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Stop-It Randomized Clinical Trial (RCT) for Intra-Abdominal Infection (IAI) Revisited: Multivariate Analyses To Identify Treatment Effects 4 Days Antibiotic Agents Versus Resolution Signs/Symptoms + 2 Days and Drivers of Outcomes.
Surg Infect (Larchmt)
December 2024
Department of Surgery, Inspira Health Network, Vineland, New Jersey, USA.
: The STOP-IT randomized clinical trial (RCT) pioneered limiting antibiotic agents in intra-abdominal infection (IAI) with adequate surgical source control, but NIH funding ended before an adequate power sample size was enrolled to determine equivalence between STOP-IT study regimens: four days of antibiotic agents (4-days) after source control versus antibiotic agents until resolution of signs and symptoms of IAI plus two days (standard of care [SOC]). The objective of this investigation was to identify possible significant treatment effects 4-days versus SOC, and independent variables defining and predicting outcomes. : De-identified data from 518 STOP-IT subjects were analyzed retrospectively in two groups: 4-days (n = 258) and SOC (n = 260), and separately as one group (n = 518).
View Article and Find Full Text PDFBreast Ironing from the Perspective of Transcultural Nursing by Madeleine Leininger: A Narrative Review.
Nurs Rep
November 2024
Department of Nursing, Faculty of Nursing, University of Valladolid, Av. Ramón y Cajal, 7, 47005 Valladolid, Spain.
(1) Background: This article addresses the harmful traditional practice of breast ironing, which primarily affects girls and adolescents in several countries, particularly in Cameroon. The practice involves applying heat and pressure to developing breasts to delay their growth, with the goal of protecting girls from sexual abuse, early pregnancy, and forced marriages. While culturally accepted, breast ironing has severe physical, psychological, and social consequences, including damage to mammary glands, pain, infections, and potential long-term health complications.
View Article and Find Full Text PDFOcular hemodynamics in multisystem inflammatory syndrome in children: A cross-sectional study.
Indian J Ophthalmol
December 2024
Division of Pediatric Infectious Disease, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye.
Purpose: To evaluate retinal vascular changes by optical coherence tomography angiography (OCTA) in multisystem inflammatory syndrome in children (MIS-C).
Methods: This cross-sectional study included 21 patients who were diagnosed with MIS-C and had a history of hospitalization, 20 pediatric outpatients with a coronavirus disease 2019 (COVID-19) diagnosis, and 26 healthy children. All patients underwent a detailed ophthalmologic examination and OCTA.
Influence of Absorber Contents and Temperatures on the Dielectric Properties and Microwave Absorbing Performances of C@TiC/SiO Composites.
Nanomaterials (Basel)
December 2024
College of Materials Science and Engineering, Nanjing Tech University, Nanjing 211816, China.
TiC provides a promising potential for high-temperature microwave absorbers due to its unique combination of thermal stability, high electrical conductivity, and robust structural integrity. C@TiC/SiO composites were successfully fabricated using a simple blending and cold-pressing method. The effects of C@TiC's absorbent content and temperature on the dielectric and microwave absorption properties of C@TiC/SiO composites were investigated.
View Article and Find Full Text PDFEffects of the Interaction of Salinity and Rare Earth Elements on the Health of : The Case of Praseodymium and Europium.
J Xenobiot
December 2024
Department of Biology & CESAM, University of Aveiro, 3810-193 Aveiro, Portugal.
The growing use of products containing rare earth elements (REEs) may lead to higher environmental emissions of these elements, which can potentially enter aquatic systems. Praseodymium (Pr) and europium (Eu) are widely used REEs with various applications. However, their ecotoxicological impacts remain largely unexplored, with poorly understood risks to wildlife.
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