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Transcriptional and Metabolomic Analyses Reveal That GmESR1 Increases Soybean Seed Protein Content Through the Phenylpropanoid Biosynthesis Pathway.
Plant Cell Environ
November 2024
National Key Laboratory of Smart Farm Technologies and Systems, College of Agriculture, Northeast Agricultural University, Harbin, Heilongjiang Province, China.
Soybeans are an economically vital food crop, which is employed as a key source of oil and plant protein globally. This study identified an EREBP-type transcription factor, GmESR1 (Enhance of Shot Regeneration). GmESR1 overexpression has been observed to significantly increase seed protein content.
View Article and Find Full Text PDFPC12 differentiation to neuron cells activated by a low-level laser at 660 nm on UV pre-treated CR-39 scaffolds with parallel microchannels.
Biomed Opt Express
August 2024
Physics Department, Amirkabir University of Technology, P.O. Box 15875-4413, Tehran, Iran.
The lack of regeneration of injured neurons in the central and peripheral neural system leads to the failure of damaged tissue repair in patients. While there is no definitive cure for most neurodegenerative diseases, new therapeutic methods that cause the proliferation and differentiation of neurons are of interest. Challenges such as the inability of neuronal cells to proliferate after injury, the lack of a stimulus for initial stimulation, and the presence of the microenvironment around CNS neurons contain several inhibitory factors that prevent neuron regeneration, thus, creating a structure similar to the extracellular matrix helps the cell proliferation in current treatment.
View Article and Find Full Text PDFIntroduction: Brachial plexus injuries (BPI) from gunshot injuries are uncommon but usually severe and can cause chronic pain, loss of function, and permanent nerve damage. Multiple surgical techniques including neurolysis, end-to-end suture repair, and graft repair have been described for the treatment of these injuries. However, surgical indication, timing, and technique for these injuries remain controversial.
View Article and Find Full Text PDFComparison of femoral bone remodeling after total hip arthroplasty with cementless short-tapered wedge stem and fully hydroxyapatite-coated stem.
Arch Orthop Trauma Surg
August 2024
Department of Orthopedic Surgery, Mie University Graduate School of Medicine, 2-174, Edobashi, 514- 8507, Tsu, Mie, Japan.
Introduction: We aimed to compare periprosthetic femoral bone remodeling after cementless total hip arthroplasty (THA) using a short-tapered wedge stem and a fully hydroxyapatite (HA)-coated stem.
Materials And Methods: In this retrospective study, 24 primary cementless THA procedures with short-tapered wedge stem and 24 using a fully HA-coated stem were performed. The follow-up duration was 2 years for both groups.
Pain Management in Staged Osseointegration Procedures: A Retrospective Study and Foundation for Future Optimization.
Mil Med
January 2025
Department of Anesthesiology, Uniformed Services University, Bethesda, MD 20814, USA.
Article Synopsis
- Osseointegration allows prosthetic devices to firmly attach to the skeleton, enhancing patients' physical function and quality of life, but research on pain management during the procedure is limited.
- A retrospective study at Walter Reed analyzed pain management in 41 patients over 76 surgeries, revealing the use of methods such as ketamine, epidurals, and nerve blocks.
- The study found that a noteworthy percentage of patients experienced increased postoperative pain, necessitating additional interventions, showcasing the complexities of managing pain effectively in such procedures.
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