A Study on Nonvibration-Exposed Organs Correlated Indices as Diagnostic Biomarkers of Hand-Arm Vibration Syndrome.

J Occup Environ Med

From the Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, China (KZ, FZ, SW, YZ, QC, HY); and Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangzhou, Guangdong Province, China (KZ, FZ, SW, YZ, QC, HY).

Published: November 2024

Objective: The aim of the study is to explore the feasibility of using nonvibration-exposed organ-related indices as vibration-induced white finger (VWF) diagnostic biomarkers.

Methods: Individuals were selected from a factory in China using the judgment sampling method. They were divided into control (con), non-VWF, and VWF groups according to the presence/absence of exposure to hand-transmitted vibration and VWF. Blood samples were collected for ELISA tests.

Results: Analysis of receiver operating characteristic curves was done on six indicators to assess their diagnostic sensitivity for VWF. Area under the receiver operating characteristic curve for insulin was 0.909 and was 0.923 for aspartate aminotransferase.

Conclusions: Insulin and aspartate aminotransferase could be used as indices for the diagnosis of hand-arm vibration syndrome.

Download full-text PDF

Source
http://dx.doi.org/10.1097/JOM.0000000000003188DOI Listing

Publication Analysis

Top Keywords

hand-arm vibration
8
vibration syndrome
8
receiver operating
8
operating characteristic
8
study nonvibration-exposed
4
nonvibration-exposed organs
4
organs correlated
4
correlated indices
4
indices diagnostic
4
diagnostic biomarkers
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!