In computational imaging and lithography, it has been a challenge for a numerical model to faithfully preserve symmetries in the physical imaging system. In this Letter, we present a project-to-symmetry-subspace (PTSS) method to prevent symmetry loss during the iterative generation of optical kernels. Essentially, PTSS is to project iterative vectors onto a predefined symmetric subspace when decomposing the transmission cross coefficient (TCC). Simulation results demonstrate the PTSS-generation of a truncated set of optical kernels that are substantially free of symmetry error, regardless of the order of truncation.
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Entropy (Basel)
January 2025
School of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, China.
Optical Coherence Tomography (OCT) is a crucial imaging modality for diagnosing and monitoring retinal diseases. However, the accurate segmentation of fluid regions and lesions remains challenging due to noise, low contrast, and blurred edges in OCT images. Although feature modeling with wide or global receptive fields offers a feasible solution, it typically leads to significant computational overhead.
View Article and Find Full Text PDFBiotechnol Prog
January 2025
Amgen, Cambridge, Massachusetts, USA.
The biopharmaceutical industry is shifting toward employing digital analytical tools for improved understanding of systems biology data and production of quality products. The implementation of these technologies can streamline the manufacturing process by enabling faster responses, reducing manual measurements, and building continuous and automated capabilities. This study discusses the use of soft sensor models for prediction of viability and viable cell density (VCD) in CHO cell culture processes by using in-line optical density and permittivity sensors.
View Article and Find Full Text PDFMed Phys
January 2025
Department of Nuclear Medicine and Medical Physics, Karolinska University Hospital, Stockholm, Sweden.
Background: Modern reconstruction algorithms for computed tomography (CT) can exhibit nonlinear properties, including non-stationarity of noise and contrast dependence of both noise and spatial resolution. Model observers have been recommended as a tool for the task-based assessment of image quality (Samei E et al., Med Phys.
View Article and Find Full Text PDFBiol Imaging
December 2024
Visual Information Laboratory, University of Bristol, Bristol, UK.
Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, offering distinct advantages and limitations. OCT offers rapid, noninvasive imaging but can suffer from clarity issues and motion artifacts, while confocal microscopy, providing high-resolution, cellular-detailed color images, is invasive and raises ethical concerns. To bridge the benefits of both modalities, we propose a novel framework based on unsupervised 3D CycleGAN for translating unpaired OCT to confocal microscopy images.
View Article and Find Full Text PDFSci Rep
January 2025
Information and Communication Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Model optimization is a problem of great concern and challenge for developing an image classification model. In image classification, selecting the appropriate hyperparameters can substantially boost the model's ability to learn intricate patterns and features from complex image data. Hyperparameter optimization helps to prevent overfitting by finding the right balance between complexity and generalization of a model.
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