AI Article Synopsis
- AE-IIPs are serious conditions linked to poor outcomes in patients with idiopathic interstitial pneumonias.
- A unique case study highlights that F-FDG PET/CT imaging was able to detect signs of AE-IIPs in a lung cancer patient just 18 days after a bronchoscopy, prior to respiratory failure.
- This report is the first to examine F-FDG PET/CT findings during the early stages of AE-IIPs, potentially enhancing our understanding of the disease’s mechanisms.
Article Abstract
Acute exacerbation of idiopathic interstitial pneumonias (AE-IIPs) is a disease associated with a poor prognosis in patients with IIPs. However, the specific characteristics of fluorine-18 2-fluoro-2-deoxy-d-glucose (F-FDG) positron emission tomography/computed tomography (PET/CT) imaging for AE-IIPs remain unclear. Herein, we present the case of a patient with lung cancer combined with IIPs who underwent F-FDG PET/CT at the early onset of AE-IIPs. The scan, conducted 18 days post-bronchoscopy for lung cancer evaluation, revealed AE-IIPs before the onset of respiratory failure. New ground-glass opacities appeared, accompanied by significant F-FDG accumulation extending beyond these regions. To the best of our knowledge, this report represents the first assessment of F-FDG PET/CT images at the early onset of AE-IIPs before respiratory failure in humans. The observed features in this PET image could potentially contribute to our understanding of the pathophysiology of AE-IIPs.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11246593 | PMC |
| http://dx.doi.org/10.1002/rcr2.1427 | DOI Listing |
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