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Enhanced Parkinson's gait, reduced fall risk, and improved cognitive function through multimodal rehabilitation combined with rivastigmine treatment. | LitMetric

AI Article Synopsis

  • - The study investigated the effects of combining rehabilitation techniques with rivastigmine treatment on motor and cognitive functions in patients with Parkinson's disease, focusing on gait performance.
  • - Fifteen patients participated in a three-week program that included various therapies and gait assessments, revealing significant improvements in walking metrics and a decrease in fall risk, while cognitive function showed a positive trend.
  • - The findings suggest that multimodal exercise interventions alongside rivastigmine can enhance balance and certain gait parameters, highlighting potential benefits for managing symptoms in Parkinson's disease patients.

Article Abstract

Objective: This study aimed to examine the effects of combined rehabilitation and rivastigmine treatment on patients with Parkinson's disease (PD).

Methods: Gait parameters were assessed using the Gibbon Gait Analyzer in fifteen patients. Baseline gait data and cognitive assessments were collected. Each patient underwent external counterpulsation therapy, transcranial magnetic stimulation therapy, and exercise therapy for one hour per day, five days a week for three weeks. Post-intervention, gait and cognitive data were re-evaluated. Alongside their standard PD medications, all participants were administered rivastigmine throughout the study period.

Results: The intervention significantly enhanced motor function in the single-task test, evidenced by marked improvements in gait metrics such as stride width and walking speed, and a substantial reduction in fall risk. Cognitive function, assessed by mini-mental state examination and Montreal cognitive assessment, showed an improvement trend after the three-week intervention. Improvements in dual-task walking function were observed, although these changes did not reach statistical significance.

Conclusion: Multimodal exercise training combined with rivastigmine treatment significantly improves certain gait parameters in the single-task test, enhances balance, and reduces the risk of falling in patients with PD. Cognitive function also demonstrated improvement.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236654PMC
http://dx.doi.org/10.62347/PAXI7650DOI Listing

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