Effects of major air pollutants on angina hospitalizations: a correlation study.

Background: Angina is a crucial risk signal for cardiovascular disease. However, few studies have evaluated the effects of ambient air pollution exposure on angina.

Objective: We aimed to explore the short-term effects of air pollution on hospitalization for angina and its lag effects.

Methods: We collected data on air pollutant concentrations and angina hospitalizations from 2013 to 2020. Distributed lag nonlinear model (DLNM) was used to evaluate the short-term effects of air pollutants on angina hospitalization under different lag structures. Stratified analysis by sex, age and season was obtained.

Results: A total of 39,110 cases of angina hospitalization were included in the study. The results showed a significant positive correlation between PM, SO, NO, and CO and angina hospitalization. Their maximum harmful effects were observed at lag0-7 (RR = 1.042; 95% CI: 1.017, 1.068), lag0-3 (RR = 1.067; 95% CI: 1.005, 1.133), lag0-6 (RR = 1.078; 95% CI: 1.041, 1.117), and lag0-6 (RR = 1.244; 95% CI: 1.109, 1.397), respectively. PM did not have an overall risk effect on angina hospitalization, but it did have a risk effect on women and the elderly. O was significantly negatively correlated with angina hospitalization, with the most pronounced effect observed at lag0-6 (RR = 0.960; 95% CI: 0.940, 0.982). Stratified analysis results showed that women and the elderly were more susceptible to pollutants, and the adverse effects of pollutants were stronger in the cold season.

Conclusion: Short-term exposure to PM, SO, NO, and CO increases the risk of hospitalization for angina.