AI Article Synopsis
- Dermatosis papulosa nigra (DPN) is a benign skin condition that impacts both physical appearance and mental well-being.
- Photodynamic therapy (PDT) has been proven effective and minimally invasive for treating various skin disorders, but its use for DPN was previously unexplored.
- In a study involving 45 patients, PDT with 10% 5-aminolevulinic acid resulted in a 71.1% cure rate and 93.3% overall efficacy, with only mild side effects like redness and temporary pigmentation.
Article Abstract
Dermatosis papulosa nigra (DPN) is a type of benign epidermal hyperplasia that affects the appearance of patients and poses a threat to their physical and mental health. Photodynamic therapy (PDT) has been shown to have the advantages of non-invasiveness, efficacy, and low recurrence in the treatment of skin disorders. However, no studies have been reported on the use of PDT for the treatment of DPN. Therefore, we used PDT for the first time to treat DPN and monitor its efficacy. Forty-five patients with DPN diagnosed at the outpatient clinic of Changzhou First People's Hospital were treated with 10 % 5-aminolevulinic acid (ALA) once a week for four consecutive weeks and followed for 3 months. After four treatment sessions, the cure rate among the 45 patients was 71.1 %, and the overall efficacy rate was 93.3 %. The most common adverse reactions were mild erythema, edema, and temporary pigmentation. PDT is expected to become a new and effective treatment for DPN.
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| http://dx.doi.org/10.1016/j.pdpdt.2024.104273 | DOI Listing |
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