AI Article Synopsis
- - The study evaluated the impact of the BioFire® FilmArray® blood culture identification panels on the time to optimal therapy (TTOT) for bacteremia caused by specific organisms at two community hospitals.
- - Results showed no significant differences in overall TTOT between groups before and after implementing the BCID panels, but BCID2 saw more timely therapy adjustments and effective carbapenem use for gram-negative bacteria.
- - There was also a notable decrease in the length of vancomycin treatment for gram-positive bacteria after BCID2 was implemented, indicating improved antimicrobial prescribing practices.
Article Abstract
The purpose of this study was to assess changes in time to optimal therapy (TTOT) for bacteremia due to select organisms after implementation of the BioFire® FilmArray® blood culture identification panels at two community teaching hospitals. TTOT (days) was similar in Pre-BCID compared to BCID1 and BCID2 [(2.48 vs. 2.65, p=0.10); (2.48 vs. 2.37, p=0.27)]. There were no significant differences in time to effective antimicrobial therapy between groups. However, there were significantly more therapy changes and appropriate carbapenem use within 24 hours of the Gram stain result for gram-negative organisms in the BCID2 arm compared to the Pre-BCID arm. Additionally, a significant reduction in the duration of vancomycin for gram-positive organisms was noted in the BCID2 arm compared to the Pre-BCID arm. These findings suggest that the incorporation of the BCID2 panel resulted in changes in prescribing practices, leading to more appropriate antimicrobial utilization in a subset of patients.
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| http://dx.doi.org/10.1016/j.diagmicrobio.2024.116384 | DOI Listing |
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