AI Article Synopsis
- Transient neonatal diabetes mellitus (TNDM) is a rare and genetically varied condition that causes high blood sugar in newborns but may resolve early in life, potentially returning later.
- A case study discusses a baby boy treated with insulin and glucose monitoring, achieving normal blood sugar levels by 2 months, despite not identifying common genetic mutations linked to TNDM.
- The report emphasizes the challenges in diagnosing TNDM and suggests that using continuous insulin and glucose monitoring can be effective and safe in managing the condition.
Article Abstract
Transient neonatal diabetes mellitus (TNDM) is a genetically heterogeneous form of neonatal diabetes characterized by hyperglycemia that remits during infancy with a tendency to recur in later life. This case report presents the history of a male infant with transient neonatal diabetes mellitus. The patient was treated with a continuous subcutaneous insulin infusion (CSII) and a continuous glucose monitoring (CGM) system until the age of 2 months, when the normoglycemia connected with a withdrawal of treatment was noted. The genetic test results excluded the majority of known mutations related to TNDM. This case report focuses on various genetic mutations and the clinical features connected with them that cause TNDM and highlights the difficulties in the diagnostic and therapeutic processes of this disease. CSII and CGM systems seem to be a safe and effective treatment option in TNDM and may be used in the therapy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11241581 | PMC |
| http://dx.doi.org/10.3390/healthcare12131257 | DOI Listing |
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